Chronic Idiopathic Myelofibrosis with Myeloid Metaplasia Presenting as Refractory Ascites

被引：3

作者：

Patra, Bijoy ^{[1
]}

Maheshwari, Anu ^{[1
]}

Chandra, Jagdish ^{[1
]}

Aneja, Satinder ^{[1
]}

Agarwal, Shilpi ^{[2
]}

Nangia, Anita ^{[2
]}

Seth, Anju ^{[1
]}

机构：

[1] Lady Hardinge Med Coll & Hosp, Dept Pediat, New Delhi, India

[2] Lady Hardinge Med Coll & Hosp, Dept Pathol, New Delhi, India

来源：

PEDIATRIC BLOOD & CANCER | 2010年 / 54卷 / 01期

关键词：

hydroxyurea; myelofibrosis; refractory ascites; PERITONEAL; HEMATOPOIESIS;

D O I：

10.1002/pbc.22274

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chronic idiopathic myelofibrosis (CIM) with myeloid metaplasia is a myeloproliferative disorder characterized by leukoerythroblastosis, tear drop erythrocytes, extra-medullary hematopoesis (EMH), and varying degree of myelofibrosis. CIM, presenting as refractory ascites secondary to peritoneal hematopoesis, is extremely rare with only six adult cases reported in literature. This is a report of a child with CIM presenting as refractory ascites as a consequence of EMH in the peritoneum. The patient was treated with intermittent hydroxyurea with favorable response over 3 weeks. The patient was thereafter lost to follow up. Pediatr Blood Cancer 2010;54:151-153. (C) 2009 Wiley-Liss, Inc.

引用

页码：151 / 153

页数：3

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