Measurement of cystatin C in capillary blood samples in pediatric patients

被引：3
|
作者：
van Deutekom, Arend W. [1 ]
Zur, Berndt [2 ]
van Wijk, Joanna A. E. [1 ]
Bouman, Anna A. [3 ]
Bokenkamp, Arend [1 ]
机构：
[1] Vrije Univ Amsterdam, Med Ctr, Dept Pediat, NL-1081 HV Amsterdam, Netherlands
[2] Univ Bonn, Med Ctr, Inst Clin Chem & Pharmacol, D-5300 Bonn, Germany
[3] Vrije Univ Amsterdam, Med Ctr, Dept Clin Chem, NL-1081 HV Amsterdam, Netherlands
来源：
CLINICAL BIOCHEMISTRY | 2010年 / 43卷 / 03期
关键词：
Cystatin-C; Capillary blood samples; Children; GLOMERULAR-FILTRATION-RATE; BETA-TRACE-PROTEIN; SERUM CREATININE; CHILDREN;
D O I：
10.1016/j.clinbiochem.2009.09.021
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
We assessed whether the GFR marker cystatin C can be measured reliably in capillary blood samples in children with renal disease. Cystatin C was measured in venous and capillary blood samples obtained simultaneously from 48 children, and GFR was estimated using the Filler equation. Estimated GFR based on capillary cystatin C concentrations was higher than the venous cystatin C based GFR. The limits of agreement between estimated GFR based on capillary and venous measurements exceeded +/-20% at the Upper reference concentration, which hampers the clinical usefulness of capillary sampling. (C) 2009 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码：335 / 337
页数：3
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