Pediatric pituitary adenomas

被引：20

作者：

Walz, Patrick C. ^{[1
,2
]}

Drapeau, Annie ^{[3
,4
]}

Shaikhouni, Ammar ^{[3
,4
]}

Eide, Jacob ^{[5
]}

Rugino, Alex J. ^{[6
]}

Mohyeldin, Ahmed ^{[3
]}

Carrau, Ricardo ^{[1
,2
,3
]}

Prevedello, Daniel ^{[3
,4
]}

机构：

[1] Ohio State Univ, Dept Otolaryngol, Wexner Med Ctr, Columbus, OH 43210 USA

[2] Nationwide Childrens Hosp, Dept Pediat Otolaryngol, 700 Childrens Dr, Columbus, OH 43205 USA

[3] Ohio State Univ, Dept Neurosurg, Wexner Med Ctr, Columbus, OH 43210 USA

[4] Nationwide Childrens Hosp, Dept Pediat Neurosurg, Columbus, OH USA

[5] Northwestern Univ, Dept Otolaryngol, Feinberg Sch Med, Chicago, IL 60611 USA

[6] OhioHlth Neurosurg, Columbus, OH USA

来源：

CHILDS NERVOUS SYSTEM | 2019年 / 35卷 / 11期

关键词：

Skull base; Pediatric; Endonasal; Pituitary adenoma; SKULL BASE SURGERY; ENDONASAL TRANSSPHENOIDAL APPROACH; NASOSEPTAL FLAP RECONSTRUCTION; CUSHINGS-DISEASE; CLINICAL PRESENTATION; TRANSCRANIAL SURGERY; CHILDREN; TUMORS; CHILDHOOD; EXPERIENCE;

D O I：

10.1007/s00381-019-04293-y

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background Pediatric pituitary adenomas are a rare medical entity that makes up a small portion of intracranial tumors in children and adolescents. Although benign, the majority of these lesions are secreting functional tumors with the potential for physiological sequela that can profoundly affect a child's development. Focus of Review In this review, we discuss the medical and surgical management of these tumors with a focus on clinical presentation, diagnostic identification, surgical approach, and associated adjuvant therapies. We will also discuss our current treatment paradigm using endoscopic, open, and combined approaches to treat these tumors. Summary The management of pituitary tumors requires a multidisciplinary team of surgeons, endocrinologists, and neuroanesthesiologists as well as neurocritical care specialists to deliver comprehensive care.

引用

页码：2107 / 2118

页数：12

共 102 条

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