Objective: To clarify the true benefits of laparoscopic-assisted colectomy by comparing clinical outcomes from a series of laparoscopic right colectomies with matched open colectomies, all performed for the singular indication of polyp not amenable to colonoscopic removal. Patients and Methods: A retrospective case-matched study nas performed of consecutive patients undergoing laparascopic-assisted right hemicolectomy for polyps between January 1992 and July 1997, Each case was matched to a control undergoing the equivalent open procedure for the same indication during the same time period. Results: Thirty-eight patients undergoing laparoscopic-assisted right hemicolectomy for polyps were identified, and matches were found. The conversion rate was 18.4% (7/38), 21.4% early in the series and 10% in later experience, Operative times were longer for laparoscopic-associated colectomy (median, 208 minutes vs 150 minutes, P<.001). Laparoscopic-assisted colectomy resulted in shorter postoperative ileus (time to flatus, 3.0 vs 4.0 days, P<.001; time to bowel movement, 3.5 vs 5.0 days, P<.001) and in earlier tolerance of regular diet (3.5 vs 6.0 days, P<.001). Fewer days of narcotic administration were required by the laparoscopic group (3.0 vs 4.5 days, P<.001). This resulted in a significantly shorter length of hospital stay (4.0 vs 7.0 days, P<.001). There was no significant difference in the incidence of postoperative complications. Conclusions: Laparoscopic right hemicolectomy has significant patient benefits. These benefits are apparent when procedures of equal complexity and equivalent indications are compared. Laparoscopic-assisted resection has become our preferred approach for polyps not amenable to colonoscopic polypectomy.