Del Nido cardioplegia in the setting of minimally invasive aortic valve surgery

被引：38
作者：
Vistarini, Nicola [1 ,2 ,3 ]
Laliberte, Eric [1 ,2 ]
Beauchamp, Philippe [1 ,2 ]
Bouhout, Ismail [1 ,2 ]
Lamarche, Yoan [1 ,2 ]
Cartier, Raymond [1 ,2 ]
Carrier, Michel [1 ,2 ]
Perrault, Louis [1 ,2 ]
Bouchard, Denis [1 ,2 ]
El-Hamamsy, Ismail [1 ,2 ]
Pellerin, Michel [1 ,2 ]
Demers, Philippe [1 ,2 ]
机构：
[1] Montreal Heart Inst, Dept Cardiac Surg, Montreal, PQ, Canada
[2] Univ Montreal, Montreal, PQ, Canada
[3] Univ Pavia, Sch Med, Dept Clin Surg Diagnost & Pediat Sci, Pavia, Italy
来源：
PERFUSION-UK | 2017年 / 32卷 / 02期
关键词：
del Nido cardioplegia; minimally invasive surgery; aortic valve; REPLACEMENT; OUTCOMES; HEART;
D O I：
10.1177/0267659116662701
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The purpose of this study is to report our experience with del Nido cardioplegia (DNC) in the setting of minimally invasive aortic valve surgery. Forty-six consecutive patients underwent minimally invasive aortic valve replacement (AVR) through a J ministernotomy: twenty-five patients received the DNC (Group 1) and 21 patients received standard blood cardioplegia (SBC) (Group 2). The rate of ventricular fibrillation at unclamping was significantly lower in the DNC group (12% vs 52%, p=0.004), as well as postoperative creatinine kinase-MB (CK-MB) values (11.4 +/- 5.2 vs 17.7 +/- 6.9 mu g/L, p=0.004). There were no deaths, myocardial infarctions or major complications in either group. Less postoperative use of intravenous insulin (28% vs 81%, p<0.001) was registered in the DNC group. In conclusion, the DNC is easy to use and safe during minimally invasive AVR, providing a myocardial protection at least equivalent to our SBC, improved surgical efficiency, minimal cost and less blood glucose perturbations.
引用
收藏
页码：112 / 117
页数：6
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