Does Rotavirus Vaccination Affect Longer-Term Intussusception Risk in US Infants?

被引:9
作者
Burke, Rachel M. [1 ,2 ]
Tate, Jacqueline E. [1 ]
Dahl, Rebecca M. [3 ]
Aliabadi, Negar [1 ]
Parashar, Umesh D. [1 ]
机构
[1] Ctr Dis Control & Prevent, Div Viral Dis, Atlanta, GA 30329 USA
[2] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30329 USA
[3] Ctr Dis Control & Prevent, Maximus Fed, Div Viral Dis, Atlanta, GA 30329 USA
关键词
immunizations; intussusception; pediatric gastroenteritis; rotavirus; rotavirus vaccine; EFFICACY; CHILDREN; SAFETY;
D O I
10.1093/jpids/piz035
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Rotavirus vaccination has been associated with a short-term increased risk of intussusception. Our analysis of insurance claims for 1 858 827 US children with 544 recorded cases of intussusception found a nonsignificant decrease in intussusception (hazard ratio, 0.79 [95% confidence interval, 0.57-1.09]) in fully rotavirus-vaccinated children followed up to the age of 2 years.
引用
收藏
页码:257 / 260
页数:4
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