Gentle drugs: A new paradigm for drug development

Searching for new drugs is guided by their specificity and potency. The methodology, including the statistical approaches, orients itself to do exactly that. More potent drugs also have more side effects, a technology trap that requires a radical re-examination regarding how to go about drug discovery. It is relevant in an era when quality of life is emerging as more important than the ill-kept promise of dramatic therapies. Interestingly, the problem statement can be formalized and a strategy can be identified that requires new methodological grounds to be covered within the scope of allopathy.