Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix

被引：1484
作者：
Guilak, Farshid [1 ,2 ]
Cohen, Daniel M. [4 ]
Estes, Bradley T. [1 ,2 ]
Gimble, Jeffrey M. [5 ]
Liedtke, Wolfgang [3 ]
Chen, Christopher S. [4 ]
机构：
[1] Duke Univ, Med Ctr, Dept Surg, Durham, NC 27710 USA
[2] Duke Univ, Med Ctr, Dept Biomed Engn, Durham, NC 27710 USA
[3] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA
[4] Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA
[5] Louisiana State Univ Syst, Pennington Biomed Res Ctr, Stem Cell Lab, Baton Rouge, LA 70808 USA
来源：
CELL STEM CELL | 2009年 / 5卷 / 01期
关键词：
MESENCHYMAL PROGENITOR CELLS; MARROW STROMAL CELLS; CYCLIC STRAIN; CHONDROGENIC DIFFERENTIATION; CA2+ ENTRY; IN-VITRO; CHONDROCYTE DIFFERENTIATION; PHENOTYPIC TRAITS; TISSUE; SHAPE;
D O I：
10.1016/j.stem.2009.06.016
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
A diverse array of environmental factors contributes to the overall control of stem cell activity. In particular, new data continue to mount on the influence of the extracellular matrix (ECM) on stem cell fate through physical interactions with cells, such as the control of cell geometry, ECM geometry/topography at the nanoscale, ECM mechanical properties, and the transmission of mechanical or other biophysical factors to the cell. Here, we review some of the physical processes by which cues from the ECM can influence stem cell fate, with particular relevance to the use of stem cells in tissue engineering and regenerative medicine.
引用
收藏
页码：17 / 26
页数：10
相关论文
共 126 条
  • [1] LOSS OF PHENOTYPIC TRAITS BY DIFFERENTIATED CELLS .3. REVERSIBLE BEHAVIOR OF CHONDROCYTES IN PRIMARY CULTURES
    ABBOTT, J
    HOLTZER, H
    [J]. JOURNAL OF CELL BIOLOGY, 1966, 28 (03) : 473 - &
  • [2] A niche opportunity for stem cell therapeutics
    Adams, G. B.
    Scadden, D. T.
    [J]. GENE THERAPY, 2008, 15 (02) : 96 - 99
  • [3] Mesenchymal stem cells: Isolation and therapeutics
    Alhadlaq, A
    Mao, JJ
    [J]. STEM CELLS AND DEVELOPMENT, 2004, 13 (04) : 436 - 448
  • [4] Cyclic hydrostatic pressure enhances the chondrogenic phenotype of human mesenchymal progenitor cells differentiated in vitro
    Angele, P
    Yoo, JU
    Smith, C
    Mansour, J
    Jepsen, KJ
    Nerlich, M
    Johnstone, B
    [J]. JOURNAL OF ORTHOPAEDIC RESEARCH, 2003, 21 (03) : 451 - 457
  • [5] Activation of integrin function by nanopatterned adhesive interfaces
    Arnold, M
    Cavalcanti-Adam, EA
    Glass, R
    Blümmel, J
    Eck, W
    Kantlehner, M
    Kessler, H
    Spatz, JP
    [J]. CHEMPHYSCHEM, 2004, 5 (03) : 383 - 388
  • [6] Advances in Tissue and Organ Replacement
    Atala, Anthony
    [J]. CURRENT STEM CELL RESEARCH & THERAPY, 2008, 3 (01) : 21 - 31
  • [7] Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds
    Awad, HA
    Wickham, MQ
    Leddy, HA
    Gimble, JM
    Guilak, F
    [J]. BIOMATERIALS, 2004, 25 (16) : 3211 - 3222
  • [8] Baharvand H, 2007, MOL VIS, V13, P1711
  • [9] β-arrestin 1 and Gαq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation
    Barnes, WG
    Reiter, E
    Violin, JD
    Ren, XR
    Milligan, G
    Lefkowitz, RJ
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (09) : 8041 - 8050
  • [10] The effect of matrix composition of 3D constructs on embryonic stem cell differentiation
    Battista, S
    Guarnieri, D
    Borselli, C
    Zeppetelli, S
    Borzacchiello, A
    Mayol, L
    Gerbasio, D
    Keene, DR
    Ambrosio, L
    Netti, PA
    [J]. BIOMATERIALS, 2005, 26 (31) : 6194 - 6207
12345678910