SPR Label-Free Biosensor with Oxide-Metal-Oxide-Coated D-Typed Optical Fiber: a Theoretical Study

被引:14
作者
Du, Bobo [1 ,2 ]
Yang, Yuan [1 ,2 ]
Zhang, Yang [1 ,2 ]
Yang, Dexing [1 ,2 ]
机构
[1] Northwestern Polytech Univ, MOE Key Lab Mat Phys & Chem Extraordinary Condit, Sch Sci, Xian 710072, Shaanxi, Peoples R China
[2] Northwestern Polytech Univ, Shaanxi Key Lab Opt Informat Technol, Xian 710072, Shaanxi, Peoples R China
关键词
D-typed optical fiber; Surface plasmon resonance; Biological sensors; Multilayer film; SURFACE-PLASMON-RESONANCE; SENSOR; GRAPHENE;
D O I
10.1007/s11468-018-0824-1
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
In this article, a surface plasmon resonance (SPR) biosensor based on D-typed optical fiber coated by Al2O3/Ag/Al2O3 film is investigated numerically. Resonance in near infrared with an optimized architecture is achieved. Refractive index sensitivity of 6558nm/RIU (refractive index unit) and detection limit of 1.5x10(-6) RIU, corresponding to 0.4357nm/M and detection limit of 23nM in BSA (bovine serum albumin) concentration sensing, are obtained. The analysis of the performance of the sensor in gaseous sensing indicates that this proposed SPR sensor is much suitable for label-free biosensing in aqueous media.
引用
收藏
页码:457 / 463
页数:7
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