Genetics of insulin-dependent diabetes; Non-major histocompatibility genes

被引:8
|
作者
Merriman, TR
Todd, JA
机构
基金
英国惠康基金;
关键词
insulin-dependent diabetes; genetics; non-MHC genes;
D O I
10.1055/s-2007-979795
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Recently, the major advances in understanding the genetics of type 1 diabetes have come using the positional cloning approach, both in mouse and human. Construction of congenic mouse strains and, in human, the exploitation of linkage disequilibrium between very closely linked markers and disease-predisposing loci, is enabling fine mapping of these loci.
引用
收藏
页码:289 / 293
页数:5
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