Enhanced Coherent anti-Stokes Raman Scattering imaging using silica mircospheres

被引：2
作者：
Huang, X. [1 ]
He, X. N. [1 ]
Xiong, W. [1 ]
Gao, Y. [1 ]
Jiang, L. J. [1 ]
Liu, L. [1 ]
Zhou, Y. S. [1 ]
Silvain, J. F. [1 ,2 ]
Jiang, L. [3 ]
Lu, Y. F. [1 ]
机构：
[1] Univ Nebraska, Dept Elect Engn, Lincoln, NE 68588 USA
[2] Univ Bordeaux 1, CNRS, ICMCB, F-33608 Pessac, France
[3] Beijing Inst Technol, Sch Mech Engn, Beijing 100081, Peoples R China
来源：
NANOSCALE IMAGING, SENSING, AND ACTUATION FOR BIOMEDICAL APPLICATIONS XI | 2014年 / 8954卷
基金：
美国国家科学基金会;
关键词：
Enhanced Coherent anti-Stokes Raman scattering; silica microspheres; FDTD simulation; MICROSPECTROSCOPY; MICROSCOPY; CELLS; LIGHT;
D O I：
10.1117/12.2041783
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
A technique was developed to achieve enhanced coherent anti-Stokes Raman scattering (CARS) imaging using self-assembled silica microspheres. In this study, a layer of optically transparent silica microspheres was self-assembled onto polymer grating samples to enhance the CARS signals. The highest enhancement of 12.5 was achieved using 6.1-mu m-diameter microspheres for C-H molecule vibration. Finite-difference time-domain (FDTD) algorithm under the perfectly matched layer boundary condition was used to simulate the enhancement using silica microspheres of different diameters.
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页数：6
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