Synthesis and modification of 4-Hydroxy-2-methyl-3-(2-chloro-2-propenyl)quinoline

被引：6

作者：

Avetisyan, A. A. ^{[1
]}

Aleksanyan, I. L. ^{[1
]}

Pivazyan, A. A. ^{[1
]}

机构：

[1] Yerevan State Univ, Yerevan 375025, Armenia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 42卷 / 05期

关键词：

D O I：

10.1134/S1070428006050150

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-Hydroxy-2-methyl-3-(2-chloro-2-propenyl)quinoline was prepared by O-allylation of 4-hydroxy-2-methylquinoline followed by the Claisen rearrangement of the 2-methyl-4-(2-chloro-2-propenyloxy)quinoline obtained. Chemical modifications of 4-hydroxy-2-methyl-3-(2-chloro-2-propenyl)quinoline resulted in the synthesis of 4-amino-2-methyl-3-(2-methyl-3-indolyl)quinoline.

引用

页码：739 / 741

页数：3

共 9 条

[1]

ALEKSANYAN IL, 1985, THESIS EREVAN

[2]

Avetisyan AA, 2005, KHIM GETEROTSIKL+, P554

[3]

AVETISYAN AA, 2004, ZH ORG KHIM, V40, P1397

[4]

BARTLETT PA, 1980, TETRAHEDRON, V36, P28

[5]

GYULBUDAGYAN LV, 1973, KHIM GETEROTSIKL+, P84

[6]

GYULBUDAGYAN LV, 1989, ARM KHIM ZH, V42, P407

[7]

GYULBUDAGYAN LV, 1983, ARM KHIM ZH, V36, P376

[8] Nucleophilic aromatic substitution of hydrogen as a tool for the synthesis of indole and quinoline derivatives [J].

Makosza, M ;

Wojciechowski, K .

HETEROCYCLES, 2001, 54 (01) :445-474

[9]

MOHAMED EA, 1995, INDIAN J CHEM B, V34, P21

← 1 →