32P Brachytherapy Conformal Source Model RIC-100 for High-Dose-Rate Treatment of Superficial Disease: Monte Carlo Calculations, Diode Measurements, and Clinical Implementation

被引：10

作者：

Cohen, Gil'ad N. ^{[1
]}

Munro, John J., III ^{[3
]}

Kirov, Assen ^{[1
]}

Losasso, Thomas ^{[1
]}

Yamada, Yoshiya ^{[2
]}

Williamson, Matthew ^{[1
]}

Dauer, Lawrence T. ^{[1
]}

Zaider, Marco ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Med Phys, New York, NY 10065 USA

[2] Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, New York, NY 10065 USA

[3] Montrose Technol Inc, N Andover, MA USA

来源：

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2014年 / 88卷 / 03期

关键词：

RECOMMENDATIONS; DOSIMETRY; PHYSICS;

D O I：

10.1016/j.ijrobp.2013.11.006

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose: A novel P-32 brachytherapy source has been in use at our institution intraoperatively for temporary radiation therapy of the spinal dura and other localized tumors. We describe the dosimetry and clinical implementation of the source. Methods and Materials: Dosimetric evaluation for the source was done with a complete set of MCNP5 Monte Carlo calculations preceding clinical implementation. In addition, the depth dose curve and dose rate were measured by use of an electron field diode to verify the Monte Carlo calculations. Calibration procedures using the diode in a custom-designed phantom to provide an absolute dose calibration and to check dose uniformity across the source area for each source before treatment were established. Results: Good agreement was established between the Monte Carlo calculations and diode measurements. Quality assurance measurements results are provided for about 100 sources used to date. Clinical source calibrations were usually within 10% of manufacturer specifications. Procedures for safe handling of the source are described. Discussion: Clinical considerations for using the source are discussed. (C) 2014 Elsevier Inc.

引用

页码：746 / 752

页数：7

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