DNA microarray analysis of transcriptional responses of mouse spinal cords to physical exercise

被引:7
|
作者
Hashimoto, Kazunori [1 ]
Honda, Akiko [2 ]
Hayashi, Yuichi [1 ]
Inuzuka, Takashi [1 ]
Satoh, Masahiko [2 ]
Hozumi, Isao [1 ]
机构
[1] Gifu Univ, Grad Sch Med, Dept Neurol & Geriatr, Gifu 5011194, Japan
[2] Aichi Gakuin Univ, Sch Pharm, Lab Pharmaceut Hlth Sci, Chikusa Ku, Nagoya, Aichi 4648650, Japan
来源
JOURNAL OF TOXICOLOGICAL SCIENCES | 2009年 / 34卷 / 04期
关键词
Exercise; Treadmill; Spinal cord; DNA microarray; Amyotrophic lateral sclerosis; AMYOTROPHIC-LATERAL-SCLEROSIS; MODEL;
D O I
10.2131/jts.34.445
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
We present herein transcriptional changes in mouse spinal cords in response to physical exercise on a treadmill using a DNA rnicroarray. By 30-min exercise, the expression of 3 genes was enhanced and expression of 29 genes reduced. By continuous 2-week exercise (30-min exercise per day), the expression of 1 gene was enhanced and expression of 13 genes reduced.
引用
收藏
页码:445 / 448
页数:4
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