The Basics of Sentinel Lymph Node Biopsy: Anatomical and Pathophysiological Considerations and Clinical Aspects

被引:32
作者
Dogan, Nasuh Utku [1 ,2 ]
Dogan, Selen [1 ]
Favero, Giovanni [3 ]
Koehler, Christhardt [3 ]
Dursun, Polat [4 ]
机构
[1] Akdeniz Univ, Dept Obstet & Gynecol, Antalya, Turkey
[2] TUBITAK Res, Ankara, Turkey
[3] Asklepios Hosp, Dept Adv Operat & Oncol Gynecol, Hamburg, Germany
[4] Baskent Univ, Dept Obstet & Gynecol, Ankara, Turkey
关键词
SQUAMOUS-CELL CARCINOMA; EARLY-STAGE ENDOMETRIAL; BREAST-CANCER PATIENTS; CERVICAL-CANCER; NEOADJUVANT CHEMOTHERAPY; AXILLARY DISSECTION; INDOCYANINE-GREEN; PARAAORTIC LYMPHADENECTOMY; LOCOREGIONAL RECURRENCE; FOLLOW-UP;
D O I
10.1155/2019/3415630
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Sentinel lymph node (SLN) is the first node to receive the drainage directly from a tumor. Detection and pathological examination of the SLN is an important oncological procedure that minimizes morbidity related to extensive nodal dissection. SLN biopsy was first reported in 1960 but took approximately 40 years to come into general practice following reports of good outcomes in patients with melanoma. After many years of observation and research on its use in various malignancies SLN biopsy has become the standard surgical treatment in patients with malignant melanoma, breast, vulvar, and cervical cancers. Along with the introduction of new technologies, such as the fluorescent dyes indocyanine green (ICG) and near-infrared fluorescence (NIR), and pathologic ultrastaging, SLN detection rate has increased and false-negative rate has decreased. This literature review aimed to present an overview of the basic concepts and clinical aspects of SLN biopsy in the light of the current research.
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页数:10
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