Synthesis, spectral correlations and antimicrobial activities of substituted 4-((E)-2-benzylidenehydrazinyl)benzonitriles

被引:0
作者
Rajarajan, M. [1 ]
Senbagam, R. [1 ]
Vijayakumar, R. [1 ]
Balaji, S. [1 ]
Manikandan, V. [1 ]
Vanangamudi, G. [1 ]
Thirunarayanan, G. [2 ]
机构
[1] Govt Arts Coll, PG & Res Dept Chem, C Mutlur 608102, Chidambaram, India
[2] Annamalai Univ, Dept Chem, Annamalainagar 608002, Tamil Nadu, India
来源
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2016年 / 55卷 / 02期
关键词
Synthesis; hydrazone compounds; spectral data; correlation study; antimicrobial activities; CRYSTAL-STRUCTURE; COMPLEXES; DERIVATIVES; POLYMERIZATION; NICKEL(II); NORBORNENE; HYDRAZONES; LIGAND; AGENTS;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A series of ten substituted hydrazones have been synthesized in good yield by condensation of 4-cyanophenyl hydrazine with various substituted benzaldehydes in the presence of acetic acid. The observed UV-Vis, IR and NMR spectral data of the products have been correlated with Hammett substituent constants and Swain-Lupton's F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis the effects of substituents on the spectral data have been discussed. The antimicrobial activities of all the synthesized hydrazones have been studied using Bauer-Kirby method.
引用
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页码:197 / 206
页数:10
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