Financial toxicity in gynecologic oncology

被引：112

作者：

Bouberhan, Sara ^{[1
,2
]}

Shea, Meghan ^{[1
,2
]}

Kennedy, Alice ^{[3
]}

Erlinger, Adrienne ^{[3
]}

Stack-Dunnbier, Hannah ^{[3
]}

Buss, Mary K. ^{[1
,2
]}

Moss, Laureen ^{[1
]}

Nolan, Kathleen ^{[3
]}

Awtrey, Christopher ^{[2
,3
]}

Dalrymple, John L. ^{[2
,3
]}

Garrett, Leslie ^{[2
,3
]}

Liu, Fong W. ^{[2
,3
]}

Hacker, Michele R. ^{[2
,3
,4
]}

Esselen, Katharine M. ^{[2
,3
]}

机构：

[1] Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA

[2] Harvard Med Sch, Boston, MA 02215 USA

[3] Beth Israel Deaconess Med Ctr, Dept Obstet & Gynecol, Boston, MA 02115 USA

[4] Harvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA

来源：

GYNECOLOGIC ONCOLOGY | 2019年 / 154卷 / 01期

基金：

美国国家卫生研究院;

关键词：

Financial toxicity; Financial burden; Gynecology oncology patients; Costs of cancer care; Patient reported outcomes; QUALITY-OF-LIFE; CANCER; BURDEN; RISK; CARE;

D O I：

10.1016/j.ygyno.2019.04.003

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Objectives. Financial toxicity is increasingly recognized as an adverse outcome of cancer treatment. Our objective was to measure financial toxicity among gynecologic oncology patients and its association with demographic and disease-related characteristics; self-reported overall health; and cost-coping strategies. Methods. Follow-up patients at a gynecologic oncology practice completed a survey including the COmprehensive Score for Financial Toxicity (COST) tool and a self-reported overall health assessment, the EQ-VAS. We abstracted disease and treatment characteristics from medical records. We dichotomized COST scores into low and high financial toxicity and assessed the correlation (r) between COST scores and self-reported health. We calculated risk ratios (RR) and 95% confidence intervals (CI) for the associations of demographic and disease-related characteristics with high financial toxicity, as well as the associations between high financial toxicity and cost coping strategies. Results. Among 240 respondents, median COST score was 29. Greater financial toxicity was correlated with worse self-reported health (r = 0.47; p < 0.001). In the crude analysis, Black or Hispanic race/ethnicity, government-sponsored health insurance, lower income, unemployment, cervical cancer and treatment with chemotherapy were associated with high financial toxicity. In the multivariable analysis, only government sponsored health insurance, lower income, and treatment with chemotherapy were significantly associated with high financial toxicity. High financial toxicity was significantly associated with all cost-coping strategies, including delaying or avoiding care (RR: 7.3; 95% CI: 2.8-19.1). Conclusions. Among highly-insured gynecologic oncology patients, many respondents reported high levels of financial toxicity. High financial toxicity was significantly associated with worse self-reported overall health and cost-coping strategies, including delaying or avoiding care. (C) 2019 Elsevier Inc. All rights reserved.

引用

页码：8 / 12

页数：5

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