Facile Bifunctional Addition of Lactones and Esters at Low Temperatures. The First Intermediates in Lactone/Ester Hydrogenations

被引：93

作者：

Takebayashi, Satoshi ^{[1
]}

Bergens, Steven H. ^{[1
]}

机构：

[1] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada

来源：

ORGANOMETALLICS | 2009年 / 28卷 / 08期

基金：

加拿大自然科学与工程研究理事会;

关键词：

ENANTIOSELECTIVE KETONE HYDROGENATION; RUTHENIUM-CATALYZED HYDROGENATION; COMPLEXES; LIGAND; REDUCTION; ALCOHOLS; CARBONYL; HYDRIDE; COORDINATION; MECHANISM;

D O I：

10.1021/om9002076

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The bifunctional addition of lactones/esters is unexpectedly facile at low temperatures. Catalytic hydrogenations of esters can be carried out under mild conditions, e.g. -20 degrees C under 4 atm of H-2, bur product inhibition slows these reactions over time.

引用

页码：2349 / 2351

页数：3

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