Complications of Intra-Arterial Chemotherapy for Retinoblastoma

被引:24
作者
Monroy, Jose Efren Gonzalez [1 ]
Orbach, Darren B. [1 ]
VanderVeen, Deborah [1 ]
机构
[1] Childrens Hosp, Boston, MA 02115 USA
关键词
Chemosurgery; chemotherapy; intra-arterial; melphalan; retinoblastoma; topotecan; OPHTHALMIC ARTERY CHEMOTHERAPY; BLUE TOE SYNDROME; INTRAOCULAR RETINOBLASTOMA; REFRACTORY RETINOBLASTOMA; MELPHALAN;
D O I
10.3109/08820538.2014.959188
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Introduction: The purpose of this paper is to perform a systematic review of the published literature on complications of intra-arterial chemothrapy (IAC) for the treatment of retinoblastoma. Materials and Methods: A literature search was performed using the Pubmed database using the terms. Complications were divided into extraocular and intraocular. Results: A total of 117 articles were found using this Pubmed search method; 35 articles were selected for review as they describe specifical complications of IAC for retinoblastoma. Avariety of extraocular and intraocular complications were reported and discussed. Discussion: IAC for the treatment of retinoblastoma is a technique that has been gaining popularity in recent years, but is not without complications. Continued research is warranted to further improve current techniques and delivery of chemotherapeutic agents into the eye.
引用
收藏
页码:429 / 433
页数:5
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