Nanocarriers for drug delivery applications

被引：262

作者：

Chamundeeswari, Munusamy ^{[1
]}

Jeslin, John ^{[1
]}

Verma, Madan Lal ^{[2
]}

机构：

[1] St Josephs Coll Engn, Chennai 600119, Tamil Nadu, India

[2] Deakin Univ, Ctr Chem & Biotechnol, Geelong, Vic 3216, Australia

来源：

ENVIRONMENTAL CHEMISTRY LETTERS | 2019年 / 17卷 / 02期

关键词：

Nanocarrier; Drug delivery; Superparamagnetism; Biomedical applications; MESOPOROUS SILICA NANOPARTICLES; RESONANCE ENERGY-TRANSFER; IN-VIVO; TARGETED DELIVERY; IRON-OXIDE; POLYMERIC NANOPARTICLES; MAGNETIC NANOPARTICLES; ENZYME IMMOBILIZATION; CARBON NANOTUBES; GOLD NANOCAGES;

D O I：

10.1007/s10311-018-00841-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nanobiotechnology research has recently provided numerous basic and applied advances in the health sector. Nanocarriers have been developed for efficient drug delivery and diagnostic tools. Nanocarrier enables an effective, targeted biomolecular interaction in order to lower side effects caused during the treatment. Here, we review the problems associated with the conventional drug development and its delivery system. The efficacy of the treatment can be improved bythe usage of efficient nanocarriers such as polymeric nanocarriers, superparamagnetic nanoparticles, quantum dot, dendrimers and lipid nanoparticles. We discuss the mechanisms of delivery. This review may aid in providing better solutions for unsolved problems that prevails with the day-to-day insilico, in vitro and in vivo drug delivery model development.

引用

页码：849 / 865

页数：17

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