Intravoxel incoherent motion magnetic resonance imaging findings in the acute phase of MELAS: a case report

被引：1

作者：

Uehara, Ryuji ^{[1
]}

Yamashita, Koji ^{[1
]}

Hiwatashi, Akio ^{[1
]}

Togao, Osamu ^{[1
]}

Kikuchi, Kazufumi ^{[1
]}

Yokoyama, Jun ^{[2
]}

Matsuse, Dai ^{[2
]}

Yoshiura, Takashi ^{[1
]}

Honda, Hiroshi ^{[1
]}

机构：

[1] Kyushu Univ, Grad Sch Med Sci, Dept Clin Radiol, Higashi Ku, Fukuoka 8128582, Japan

[2] Kyushu Univ, Grad Sch Med Sci, Dept Neurol, Higashi Ku, Fukuoka 8128582, Japan

来源：

BRAIN AND BEHAVIOR | 2014年 / 4卷 / 06期

关键词：

Diffusion MRI; IVIM; MELAS; perfusion MRI; DIFFUSION; PERFUSION; STROKE;

D O I：

10.1002/brb3.282

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Objective: We report the clinical application of intravoxel incoherent motion (IVIM) magnetic resonance (MR) imaging to diagnose a case of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) in the acute phase. Results: On IVIM MR Images of this patient, higher perfusion (f) and diffusion (D) values in the left occipital and temporal lobes were found compared to the contralateral areas. Conclusion: These findings imply a breakdown of autoregulation with hyperperfusion and vasogenic edema during the acute phase of MELAS, as described in previous reports. IVIM imaging is a valuable, noninvasive tool that simultaneously quantifies perfusion and diffusion parameters.

引用

页码：798 / 800

页数：3

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