A novel phenanthrenolide and C-benzyl dihydrochalcones from Uvaria puguensis

被引：11

作者：

Makangara, JJ ^{[1
]}

Jonker, SA ^{[1
]}

Nkunya, MHH ^{[1
]}

机构：

[1] Univ Dar Es Salaam, Dept Chem, Dar Es Salaam, Tanzania

来源：

NATURAL PRODUCT LETTERS | 2002年 / 16卷 / 04期

关键词：

Uvaria puguensis; Annonaceae; isoangoletin; puguenolide; 6-hydroxy-3-methoxy-4-oxapyren-5-one; antimalarial activity;

D O I：

10.1080/10575630290020604

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new natural products, the phenanthrenoid puguenolide (6-hydroxy-3-methoxy-4-oxapyren-5-one) and isoangoletin were isolated from the stem bark of the newly described Uvaria species, U. puguensis D.M. Johnson, together with the sesquiterpene guaiol and the usual C-benzyldihydrochalcones previously found in the genus Uvaria, viz. uvaretin, diuvaretin, chamuvaritin and a mixture of triuvaretin and isotriuvaretin. Structural elucidation was achieved through a combination of spectroscopic methods.

引用

页码：267 / 272

页数：6

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