Eosinophilic Esophagitis Historical Perspective on an Evolving Disease

被引：22

作者：

Attwood, Stephen E. ^{[1
]}

Furuta, Glenn T. ^{[2
]}

机构：

[1] North Tyneside Hosp, North Shields NE29 8NH, Tyne & Wear, England

[2] Childrens Hosp Colorado, Gastrointestinal Eosinophil Dis Program, Aurora, CO 80045 USA

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2014年 / 43卷 / 02期

关键词：

Eosinophilic esophagitis; Eosinophilic oesophagitis; Dysphagia; Food bolus obstruction; GASTROESOPHAGEAL-REFLUX DISEASE; THYMIC STROMAL LYMPHOPOIETIN; ORAL VISCOUS BUDESONIDE; FOOD IMPACTION; SWALLOWED FLUTICASONE; HISTOLOGIC-FINDINGS; GENE-EXPRESSION; INTRAEPITHELIAL EOSINOPHILS; INCREASING PREVALENCE; BOERHAAVES-SYNDROME;

D O I：

10.1016/j.gtc.2014.02.010

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Initial case series describing children and adults with symptoms related to esophageal dysfunction and dense esophageal eosinophilia lead to recognition of a "new" disease, eosinophilic esophagitis (EoE). Clinical, basic, and translational studies have provided a deeper understanding of this somewhat enigmatic disease that mechanistically is defined as an antigen-driven condition limited to the esophagus. This article summarizes many of the key historical features of EoE and provides a glimpse of potential future developments.

引用

页码：185 / +

页数：16

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