Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015: Findings from the Global Burden of Disease 2015 study

被引：12

作者：

Mokdad, Ali H. ^{[2
]}

Khalil, Ibrahim ^{[2
]}

El Bcheraoui, Charbel ^{[2
]}

Charara, Raghid ^{[3
]}

Moradi-Lakeh, Maziar ^{[4
]}

Afshin, Ashkan ^{[2
,5
]}

Kassebaum, Nicholas J. ^{[2
]}

Collison, Michael ^{[2
]}

Chew, Adrienne ^{[2
]}

Krohn, Kristopher J. ^{[2
]}

Daoud, Farah ^{[2
]}

Colombara, Danny

Foreman, Kyle J. ^{[2
,6
]}

Godwin, William W. ^{[1
]}

Kutz, Michael ^{[1
]}

Mirarefin, Mojde ^{[1
,7
]}

Rao, Puja C. ^{[2
]}

Reiner, Robert, Jr. ^{[2
]}

Troeger, Christopher ^{[2
]}

Wang, Haidong ^{[2
]}

Abraha, Haftom Niguse ^{[8
]}

Abu-Elyazeed, Remon ^{[9
]}

Abu-Raddad, Laith J. ^{[10
]}

Kiadaliri, Aliasghar Ahmad ^{[11
]}

Ahmadi, Alireza ^{[12
]}

Ahmed, Muktar Beshir ^{[13
]}

Alam, Khurshid ^{[14
,15
,16
]}

Alizadeh-Navaei, Reza ^{[17
]}

Al-Raddadi, Rajaa ^{[18
]}

Altirkawi, Khalid A. ^{[19
]}

Alvis-Guzman, Nelson ^{[20
]}

Anber, Nahla ^{[21
]}

Anwari, Palwasha

Atey, Tesfay Mehari ^{[8
]}

Avokpaho, Euripide Frinel G. Arthur ^{[22
,23
]}

Bacha, Umar ^{[24
]}

Bazargan-Hejazi, Shahrzad ^{[25
,26
]}

Geffen, David

Bedi, Neeraj ^{[27
]}

Bensenor, Isabela M. ^{[28
]}

Berhane, Adugnaw ^{[29
]}

Bessong, Pascal Obong ^{[30
]}

Beyene, Addisu Shunu ^{[31
]}

Bhutta, Zulfiqar A. ^{[32
,33
]}

Buckle, Geoffrey Colin ^{[34
]}

Butt, Zahid A. ^{[35
]}

Danawi, Hadi ^{[36
]}

Deribew, Amare ^{[37
,38
]}

Djalalinia, Shirin ^{[39
]}

Dubey, Manisha ^{[40
]}

机构：

[1] Inst Hlth Metr & Evaluat, 2301 5th Ave,Suite 600, Seattle, WA 98121 USA

[2] Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA

[3] Amer Univ Beirut, Beirut, Lebanon

[4] Iran Univ Med Sci, Gastrointestinal & Liver Dis Res Ctr GILDRC, Prevent Med & Publ Hlth Res Ctr, Dept Community Med, Tehran, Iran

[5] Seattle Childrens Hosp, Dept Anesthesiol & Pain Med, Seattle, WA USA

[6] Imperial Coll London, London, England

[7] Hunger Action Los Angeles, Los Angeles, CA USA

[8] Mekelle Univ, Mekelle, Ethiopia

[9] GlaxoSmithKline Vaccines, Philadelphia, PA USA

[10] Weill Cornell Med Coll Qatar, Infect Dis Epidemiol Grp, Doha, Qatar

[11] Lund Univ, Dept Clin Sci Lund, Clin Epidemiol Unit, Orthoped, Lund, Sweden

[12] Kermanshah Univ Med Sci, Kermanshah, Iran

[13] Jimma Univ, Dept Epidemiol, Coll Hlth Sci, Jimma, Ethiopia

[14] Univ Melbourne, Murdoch Childrens Res Inst, Parkville, Vic, Australia

[15] Univ Melbourne, Melbourne, Vic, Australia

[16] Univ Sydney, Sydney, NSW, Australia

[17] Mazandaran Univ Med Sci, Gastrointestinal Canc Res Ctr, Sari, Iran

[18] Joint Program Family & Community Med, Jeddah, Makkah, Saudi Arabia

[19] King Saud Univ, Riyadh, Saudi Arabia

[20] Univ Cartagena, Cartagena De Indias, Colombia

[21] Mansoura Univ, Mansoura, Egypt

[22] IRCB, Cotonou, Benin

[23] LERAS Afrique, Parakou, Benin

[24] Univ Management & Technol, Sch Hlth Sci, Lahore, Pakistan

[25] Charles R Drew Univ Med & Sci, Coll Med, 1621 E 120th St, Los Angeles, CA 90059 USA

[26] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA

[27] Coll Publ Hlth & Trop Med, Jazan, Saudi Arabia

[28] Univ Sao Paulo, Sao Paulo, Brazil

[29] Debre Berhan Univ, Coll Hlth Sci, Debre Berhan, Ethiopia

[30] Univ Venda, Thohoyandou, South Africa

[31] Haramaya Univ, Coll Hlth & Med Sci, Harar, Ethiopia

[32] Aga Khan Univ, Ctr Excellence Women & Child Hlth, Karachi, Pakistan

[33] Hosp Sick Children, Ctr Global Child Hlth, Toronto, ON, Canada

[34] Univ Calif San Francisco, San Francisco, CA USA

[35] Al Shifa Trust Eye Hosp, Rawalpindi, Pakistan

[36] Walden Univ, Minneapolis, MN USA

[37] Univ Oxford, Nuffield Dept Med, Oxford, England

[38] KEMRI Wellcome Trust Res Programme, Kilifi, Kenya

[39] Undersecretary Res & Technol, Minist Hlth & Med Educ, Tehran, Iran

[40] Int Inst Populat Sci, Bombay, Maharashtra, India

[41] Arba Minch Univ, Arba Minch, Ethiopia

[42] Minist Hlth & Med Educ, Tehran, Iran

[43] Arak Univ Med Sci, Arak, Iran

[44] Karolinska Inst, Dept Neurobiol Care Sci & Soc NVS, Stockholm, Sweden

[45] Bielefeld Univ, Sch Publ Hlth, Bielefeld, Germany

[46] Jimma Univ, Jimma, Ethiopia

[47] St James Sch Med, Dept Microbiol, The Quarter, Anguilla

[48] St James Sch Med, Dept Epidemiol & Biostat, The Quarter, Anguilla

[49] Arabian Gulf Univ, Manama, Bahrain

[50] Hamdan Bin Mohammed Smart Univ, Dubai, U Arab Emirates

来源：

INTERNATIONAL JOURNAL OF PUBLIC HEALTH | 2018年 / 63卷

基金：

比尔及梅琳达.盖茨基金会;

关键词：

Eastern Mediterranean Region; Burden of disease; Diarrheal diseases; COST-EFFECTIVENESS; COUNTRIES; IMMUNIZATION; CHILDREN; HEALTH; IMPACT; GEMS;

D O I：

10.1007/s00038-017-1008-z

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children's potential livelihood through growth faltering, cognitive impairment, and other sequelae. As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)-the sum of years of life lost and years lived with disability-for both sexes and all ages. We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018-124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4-19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640-79,486). DALYs per 100,000 ranged from 304 (95% UI 228-400) in Kuwait to 38,900 (95% UI 25,900-54,300) in Somalia. Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.

引用

页码：109 / 121

页数：13

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