Enantiomerically pure cyclopropane building blocks: Synthesis and transformations of 2-iodocyclopropylboronic esters

被引：34

作者：

Hohn, E ^{[1
]}

Pietruszka, J ^{[1
]}

机构：

[1] Univ Stuttgart, Inst Organ Chem, D-70569 Stuttgart, Germany

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2004年 / 346卷 / 07期

关键词：

boron; chiral auxiliaries; cross-coupling; cyclopropanes; palladium;

D O I：

10.1002/adsc.200404055

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Enantiomerically pure 2-iodocyclopropyl-boronic esters 6 and 8 have been synthesized from the readily available allylic alcohol 2 via an oxidation-radical decarboxylation sequence. These unique building blocks have been demonstrated to be versatile intermediates for a consecutive Suzuki-coupling with aryl-, heteroaryl-, alkenyl-, and cyclopropylboron derivatives (I example each).

引用

页码：863 / 866

页数：4

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