Neural Tube Defects in Malaysia: Data from the Malaysian National Neonatal Registry

被引:12
|
作者
Boo, Nem-Yun [1 ]
Cheah, Irene G. S. [2 ]
Thong, Meow-Keong [3 ]
机构
[1] Univ Tunku Abdul Rahman, Fac Med & Hlth Sci, Kajang 43000, Selangor, Malaysia
[2] Hosp Kuala Lumpur, Paediat Inst, Dept Paediat, Kuala Lumpur 50586, Malaysia
[3] Univ Malaya, Dept Paediat, Fac Med, Kuala Lumpur 50603, Malaysia
关键词
neural tube defects; Malaysia; POPULATION; PREVENTION; PREVALENCE; ANOMALIES; ENGLAND; DIETARY; FOLATE;
D O I
10.1093/tropej/fmt026
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
This study aimed to determine the prevalence and early outcome of neural tube defects (NTDs) in Malaysia. This prospective study included all neonates with NTDs (spina bifida, anencephaly, encephalocoele) born in 2009 in 32 Malaysian hospitals in the Malaysian National Neonatal Network. The prevalence of NTDs was 0.42 per 1000 live births, being highest among the indigenous people of Sarawak (1.09 per 1000 live births) and lowest among Malaysians of Chinese descent (0.09 per 1000 live births). The most common type of NTDs was anencephaly (0.19 per 1000 live births), followed by spina bifida (0.11 per 1000 live births) and encephalocoele (0.07 per 1000 live births). Majority of the infants with anencephaly (94.5%, n = 51), 45.8% (n = 11) with encephalocoele and 9.5% (n = 4) with spina bifida died. The median duration of hospital stay was 4 (range: 0-161) days. Conclusion: NTDs were common in Malaysia. Mortality was high. Long-term monitoring of NTD prevalence following folic fortification of food is recommended.
引用
收藏
页码:338 / 342
页数:5
相关论文
共 50 条
  • [31] Diabetes and Obesity-Related Genes and the Risk of Neural Tube Defects in the National Birth Defects Prevention Study
    Lupo, Philip J.
    Canfield, Mark A.
    Chapa, Claudia
    Lu, Wei
    Agopian, A. J.
    Mitchell, Laura E.
    Shaw, Gary M.
    Waller, D. Kim
    Olshan, Andrew F.
    Finnell, Richard H.
    Zhu, Huiping
    AMERICAN JOURNAL OF EPIDEMIOLOGY, 2012, 176 (12) : 1101 - 1109
  • [32] Primary Immunodeficiencies in Russia: Data From the National Registry
    Mukhina, Anna A.
    Kuzmenko, Natalya B.
    Rodina, Yulia A.
    Kondratenko, Irina V.
    Bologov, Andrei A.
    Latysheva, Tatiana V.
    Prodeus, Andrei P.
    Pampura, Alexander N.
    Balashov, Dmitrii N.
    Ilyina, Natalya I.
    Latysheva, Elena A.
    Deordieva, Ekaterina A.
    Shvets, Oksana A.
    Deripapa, Elena V.
    Abramova, Irina N.
    Pashenko, Olga E.
    Vahlyarskaya, Svetlana S.
    Zinovyeva, Natalya V.
    Zimin, Sergei B.
    Skorobogatova, Elena V.
    Machneva, Elena B.
    Fomina, Daria S.
    Ipatova, Maria G.
    Barycheva, Ludmila Yu.
    Khachirova, Ludmila S.
    Tuzankina, Irina A.
    Bolkov, Michail A.
    Shakhova, Natalya V.
    Kamaltynova, Elena M.
    Sibgatullina, Farida I.
    Guseva, Marina N.
    Kuznetsova, Raisa N.
    Milichkina, Anzhelika M.
    Totolian, Areg A.
    Kalinina, Natalia M.
    Goltsman, Evgenia A.
    Sulima, Ekatherina I.
    Kutlyanceva, Anastasia Yu.
    Moiseeva, Anna A.
    Khoreva, Anna L.
    Nesterenko, Zoya
    Tymofeeva, Elena V.
    Ermakova, A.
    Proligina, Dilyara D.
    Kalmetieva, Linara R.
    Davletbaieva, Gulshat A.
    Mirsayapova, Irina A.
    Richkova, Olga A.
    Kuzmicheva, Ksenia P.
    Grakhova, Maria A.
    FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [33] Risk Factors for Neural-Tube Defects Detected in Utero: A Prospective Community-Based Study from Addis Ababa
    Tirsit, Abenezer
    Yigaramu, Mahlet
    Zewdneh, Daniel
    Kucha, Winner
    Hagos, Seifu
    Shikur, Bilal
    Laeke, Tsegazeab
    Moen, Bente E.
    Lie, Rolv T.
    Lund-Johansen, Morten
    Mahesparan, Rupavathana
    WORLD NEUROSURGERY, 2024, 185 : E683 - E690
  • [34] Nitrosatable Drug Exposure During Early Pregnancy and Neural Tube Defects in Offspring National Birth Defects Prevention Study
    Brender, Jean D.
    Werler, Martha M.
    Kelley, Katherine E.
    Vuong, Ann M.
    Shinde, Mayura U.
    Zheng, Qi
    Huber, John C., Jr.
    Sharkey, Joseph R.
    Griesenbeck, John S.
    Romitti, Paul A.
    Langlois, Peter H.
    Suarez, Lucina
    Canfield, Mark A.
    AMERICAN JOURNAL OF EPIDEMIOLOGY, 2011, 174 (11) : 1286 - 1295
  • [35] Association between maternal periconceptional alcohol consumption and neural tube defects: Findings from the National Birth Defects Prevention Study, 1997-2011
    Louden, Adia R.
    Suhl, Jonathan
    Kancherla, Vijaya
    Conway, Kristin M. Caspers
    Makelarski, Jennifer
    Howley, Meredith M.
    Hoyt, Adrienne T.
    Olney, Richard S.
    Olshan, Andrew F.
    Romitti, Paul A.
    BIRTH DEFECTS RESEARCH, 2020, 112 (05): : 427 - 439
  • [36] Maternal, paternal, and neonatal risk factors for neural tube defects: A systematic review and meta-analysis
    Jia, Shanshan
    Wei, Xiaowei
    Ma, Ling
    Wang, Yanfu
    Gu, Hui
    Liu, Dan
    Ma, Wei
    Yuan, Zhengwei
    INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, 2019, 78 : 227 - 235
  • [37] Neonatal ten-year retrospective study on neural tube defects in a second level University Hospital
    Piro, Ettore
    Serra, Gregorio
    Schierz, Ingrid Anne Mandy
    Giuffre, Mario
    Corsello, Giovanni
    ITALIAN JOURNAL OF PEDIATRICS, 2020, 46 (01)
  • [38] Neonatal ten-year retrospective study on neural tube defects in a second level University Hospital
    Ettore Piro
    Gregorio Serra
    Ingrid Anne Mandy Schierz
    Mario Giuffrè
    Giovanni Corsello
    Italian Journal of Pediatrics, 46
  • [39] Folic acid prevents more than neural tube defects: A registry-based study in the northern Netherlands
    de Walle, HEK
    Reefhuis, J
    Cornel, MC
    EUROPEAN JOURNAL OF EPIDEMIOLOGY, 2003, 18 (03) : 279 - 280
  • [40] Data to the Malaysian liverwort flora, III: New Lejeuneaceae records from Sabah and Peninsular Malaysia
    Sarimi, Muhammad Syafiq
    Pocs, Tamas
    Lee, Gaik Ee
    CRYPTOGAMIE BRYOLOGIE, 2021, 42 (19) : 249 - 267