DOWNREGULATION OF FERRITIN HEAVY CHAIN INCREASES LABILE IRON POOL, OXIDATIVE STRESS AND CELL DEATH IN CARDIOMYOCYTES

被引:0
|
作者
Omiya, Shigemiki [1 ]
Hikoso, Shungo [1 ]
Otsu, Kinya [1 ]
机构
[1] Osaka Univ, Grad Sch Med, Dept Cardiovasc Med, Suita, Osaka 565, Japan
来源
关键词
D O I
暂无
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
引用
收藏
页码:315 / 315
页数:1
相关论文
共 50 条
  • [31] CELLULAR POOL OF TRANSIENT FERRIC IRON, CHELATABLE BY DEFEROXAMINE AND DISTINCT FROM FERRITIN, THAT IS INVOLVED IN OXIDATIVE CELL INJURY
    ROTHMAN, RJ
    SERRONI, A
    FARBER, JL
    MOLECULAR PHARMACOLOGY, 1992, 42 (04) : 703 - 710
  • [32] Phosphoinositide-3-kinase inhibition elevates ferritin level resulting depletion of labile iron pool and blocking of glioma cell proliferation
    Gupta, Poonam
    Singh, Pratibha
    Pandey, Hriday S.
    Seth, Pankaj
    Mukhopadhyay, Chinmay K.
    BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2019, 1863 (03): : 547 - 564
  • [33] Amyloid light chain increases brain natriuretic peptide (BNP) expression and induces oxidative stress response in cardiomyocytes
    Tam, S. J. Stephen
    Li, L.
    Renz, M.
    Dolan, P. J.
    Nijjar, T.
    Goldbach, E.
    Kinney, G. G.
    Zago, W.
    EUROPEAN JOURNAL OF HEART FAILURE, 2017, 19 : 600 - 600
  • [34] Fluvastatin suppresses hemin-induced cell death, reactive oxygen species generation, and elevated labile iron pool
    Imoto, Shion
    Saigo, Katsuyasu
    Kono, Mari
    Ohbuchi, Ayako
    Sawamura, Tohru
    Mizokoshi, Yuji
    Suzuki, Takashi
    HEMATOLOGY TRANSFUSION AND CELL THERAPY, 2024, 46 : S284 - S290
  • [35] Fluvastatin suppresses hemin-induced cell death, reactive oxygen species generation, and elevated labile iron pool
    Imoto, Shion
    Saigo, Katsuyasu
    Kono, Mari
    Ohbuchi, Ayako
    Sawamura, Tohru
    Mizokoshi, Yuji
    Suzuki, Takashi
    HEMATOLOGY TRANSFUSION AND CELL THERAPY, 2024, 46 : S284 - S290
  • [36] Conditional Overexpression of Ferritin Heavy Chain Sequesters Intracellular Iron to Promote Replication Stress in Lung Cancer Cells
    Bayanbold, Khaliunaa
    Petronek, Michael
    Fath, Melissa
    Henrich, John B.
    Stolwijk, Jeffrey
    Kalen, Amanda
    Goswami, Prabhat
    Spitz, Doug
    FREE RADICAL BIOLOGY AND MEDICINE, 2022, 180 : 58 - 59
  • [37] Artesunate induces ER-derived-ROS-mediated cell death by disrupting labile iron pool and iron redistribution in hepatocellular carcinoma cells
    Jiang, Zhongyong
    Wang, Ziwen
    Chen, Long
    Zhang, Chi
    Liao, Fengying
    Wang, Yawei
    Wang, Yang
    Luo, Peng
    Luo, Min
    Shi, Chunmeng
    AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 11 (03): : 691 - +
  • [38] Red blood cells upregulate cytoprotective proteins and the labile iron pool in dividing human T cells despite a reduction in oxidative stress
    Fonseca, AM
    Pereira, CF
    Porto, G
    Arosa, FA
    FREE RADICAL BIOLOGY AND MEDICINE, 2003, 35 (11) : 1404 - 1416
  • [39] Endothelial nitric oxide synthase induced by doxorubicin in cardiomyocytes contributes to oxidative stress and apoptotic cell death
    Konorev, EA
    Shi, Y
    Kotamraju, S
    Kalivendi, S
    Pritchard, KA
    Baker, JE
    Kalyanaraman, B
    CIRCULATION, 2001, 104 (17) : 94 - 94
  • [40] Downregulation of NF-κB signaling by mutant huntingtin proteins induces oxidative stress and cell death
    Reijonen, Sami
    Kukkonen, Jyrki P.
    Hyrskyluoto, Alise
    Kivinen, Jenny
    Kairisalo, Minna
    Takei, Nobuyuki
    Lindholm, Dan
    Korhonen, Laura
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2010, 67 (11) : 1929 - 1941