Modification of biological properties of amino acids by electron-beam plasma treatment

被引：5

作者：

Vasil'ev, M. N. ^{[1
]}

Vasil'eva, T. M. ^{[1
]}

机构：

[1] Moscow Phys Tech Inst, Dolgoprudnyi 141700, Russia

来源：

HIGH ENERGY CHEMISTRY | 2006年 / 40卷 / 06期

关键词：

Platelet Aggregation; Vasil; High Energy Chemistry; Electron Energy Distribution Function; Plasma Cloud;

D O I：

10.1134/S0018143906060117

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The feasibility of modifying by beam-plasma treatment the biological activity of substances classified with amino acids and proteins was examined, and a possibility for controlling the modification process by varying treatment conditions was shown. An untreated synthetic alanine derivative did not affect platelet aggregation. After plasma treatment, the modification product of the alanine derivative reduced the platelet activity by more than a factor of 2. The products of modification of a fibrin monomer decreased the platelet aggregation by a factor of 1.5 on average, whereas the untreated fibrin monomer had no effect on the process.

引用

页码：421 / 425

页数：5