Cytotoxic Triterpenoids from the Rhizomes of Astilbe chinensis

被引：12

作者：

Cai, Xing-Fu ^{[1
]}

Park, Bo-Young ^{[1
]}

Ahn, Kyung-Seop ^{[1
]}

Kwon, Ok-Kyoung ^{[1
]}

Lee, Hyeong-Kyu ^{[1
]}

Oh, Sei-Ryang ^{[1
]}

机构：

[1] Korea Res Inst Biosci & Biotechnol, Immune Modulator Res Ctr, Taejon 305806, South Korea

来源：

JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 07期

关键词：

HELA-CELLS; ACID; APOPTOSIS; INDUCTION;

D O I：

10.1021/np900028v

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Six new triterpenoids (1-6) with a carboxylic acid functionality at C-27 were isolated from the rhizomes of a Korean native perennial herb, Astilbe chinensis, along with nine known triterpenoids. The structures of 1-6 were elucidated on the basis of spectroscopic data interpretation. All compounds isolated were evaluated for cytotoxic effects against a small panel of human cancer lines.

引用

页码：1241 / 1244

页数：4

共 20 条

[1] NEW POLYHYDROXYLATED TRITERPENES FROM UNCARIA-TOMENTOSA
AQUINO, R
DESIMONE, F
VINCIERI, FF
PIZZA, C
GACSBAITZ, E
[J]. JOURNAL OF NATURAL PRODUCTS, 1990, 53 (03): : 559 - 564
[2] CHEN PF, 1996, ACTA PHARMACOL SIN, V21, P302
[3] ANT-REPELLENT TRITERPENOIDS FROM CORDIA-ALLIODORA
CHEN, TK
ALES, DC
BAENZIGER, NC
WIEMER, DF
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1983, 48 (20) : 3525 - 3531
[4] Regulation of TM4SF5-mediated tumorigenesis through induction of cell detachment and death by tiarellic acid
Choi, Suyong
Oh, Sei-Ryang
Lee, Sin-Ae
Lee, Sung-Yul
Ahn, Kyungseop
Lee, Hyeong-Kyu
Lee, Jung Weon
[J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2008, 1783 (09): : 1632 - 1641
[5] Hu JY, 2006, CHINESE CHEM LETT, V17, P628
[6] 2β,24-Dihydroxyurs-12-en-27-oic acid methanol solvate from the rhizome of Astilbe chinensis
Hu, Jun-Yi
Yao, Zhi
Xu, Ying-Qian
Liu, Pu
Duan, Hong-Quan
[J]. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O2375 - O2377
[7] Antiinflammatory activity of astilbic acid from Astilbe chinensis
Moon, TC
Lin, CX
Lee, JS
Kim, DS
Bae, K
Son, KH
Kim, HP
Kang, SS
Son, JK
Chang, HW
[J]. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2005, 28 (01) : 24 - 26
[8] RAPID COLORIMETRIC ASSAY FOR CELLULAR GROWTH AND SURVIVAL - APPLICATION TO PROLIFERATION AND CYTO-TOXICITY ASSAYS
MOSMANN, T
[J]. JOURNAL OF IMMUNOLOGICAL METHODS, 1983, 65 (1-2) : 55 - 63
[9] Effect of the rhizomes of Astilbe chinensis on UVB-induced inflammatory response
Na, MK
Min, BS
An, RB
Jin, WY
Kim, YH
Song, KS
Seong, YH
Bae, KH
[J]. PHYTOTHERAPY RESEARCH, 2004, 18 (12) : 1000 - 1004
[10] Pan JT, 1985, ACTA PHYTOTAXONOMICA, V23, P432

← 1 2 →