The genome of a clinical Klebsiella variicola strain reveals virulence-associated traits and a pl9-like plasmid

被引：28
作者：
Andrade, Bruno Gabriel N. [1 ]
Ramos, Nilceia de Veiga [1 ]
Abanto Marin, Michel F. [1 ]
Fonseca, Erica L. [1 ]
Vicente, Ana Carolina P. [1 ]
机构：
[1] Fiocruz MS, Inst Oswaldo Cruz, Lab Genet Mol Microorganismos, BR-21045900 Rio De Janeiro, Brazil
来源：
FEMS MICROBIOLOGY LETTERS | 2014年 / 360卷 / 01期
关键词：
Klebsiella virulence determinants; mobilome; penicillin resistant; whole genome sequencing; FIMBRIAE; TYPE-1; GENES;
D O I：
10.1111/1574-6968.12583
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Klebsiella species frequently cause clinically relevant human infections worldwide. We report the draft genome sequence of a Brazilian clinical isolate (Bz19) of the recently recognized species Klebsiella variicola. The comparison of Bz19 genome content with the At-22 (environmental K.variicola) and several clinical Klebsiella pneumoniae shows that these species share a set of virulence-associated determinants. Of note, this K.variicola strain harbours a plasmid-like element that shares the same backbone present in a multidrug-resistant plasmid found in a clinical K.pneumoniae isolated in USA.
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页码：13 / 16
页数：4
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