The genome of a clinical Klebsiella variicola strain reveals virulence-associated traits and a pl9-like plasmid

被引：28

作者：

Andrade, Bruno Gabriel N. ^{[1
]}

Ramos, Nilceia de Veiga ^{[1
]}

Abanto Marin, Michel F. ^{[1
]}

Fonseca, Erica L. ^{[1
]}

Vicente, Ana Carolina P. ^{[1
]}

机构：

[1] Fiocruz MS, Inst Oswaldo Cruz, Lab Genet Mol Microorganismos, BR-21045900 Rio De Janeiro, Brazil

来源：

FEMS MICROBIOLOGY LETTERS | 2014年 / 360卷 / 01期

关键词：

Klebsiella virulence determinants; mobilome; penicillin resistant; whole genome sequencing; FIMBRIAE; TYPE-1; GENES;

D O I：

10.1111/1574-6968.12583

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Klebsiella species frequently cause clinically relevant human infections worldwide. We report the draft genome sequence of a Brazilian clinical isolate (Bz19) of the recently recognized species Klebsiella variicola. The comparison of Bz19 genome content with the At-22 (environmental K.variicola) and several clinical Klebsiella pneumoniae shows that these species share a set of virulence-associated determinants. Of note, this K.variicola strain harbours a plasmid-like element that shares the same backbone present in a multidrug-resistant plasmid found in a clinical K.pneumoniae isolated in USA.

引用

页码：13 / 16

页数：4

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