Combined microwave thermal ablation and liver resection for single step treatment of otherwise unresectable colorectal liver metastases; a monoistitutional experiences

被引:0
作者
Tropea, A. [1 ]
Biondi, A. [1 ]
Corsaro, A. [1 ]
Donati, M. [1 ]
Basile, F. [1 ]
Gruttadauria, S. [1 ,2 ]
机构
[1] Univ Catania, Dept Gen Surg, Catania, Italy
[2] UPMC ISMETT, Palermo, Italy
关键词
Liver metastasis; Colorectal cancer; Microwave; Thermal ablation; Liver resection;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
OBJECTIVE: Over half of colorectal cancer patients will develop liver metastases. BACKGROUND: Thermal ablation with or without associated liver resection for colorectal hepatic metastasis has been suggested as an alternative method to improve survival if radical surgical resection is not achievable. A retrospective case series of patients treated with microwave ablation(MWA) associated with hepatic resection in one step procedure, was reviewed to analyze the clinical outcome. MATERIALS AND METHODS: In a group of 40 patients surgically cured for liver tumors in our Department, 5 patients with technically unresectable disease underwent combined treatment LR-MWA. RESULTS: Four patients were treated with multiple segmentectomies and MWA and one patient received a left lobectomy (S2-S3) and MWA. Only 1 patient (20%) developed post surgical complication which was a liver abscess (grade II of Dindo classification). CONCLUSIONS: Hepatic resection combined with MWA expanded indications for operative treatment of multiple bilobar liver metastasis. This procedure promise to have good long-term outcomes.
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页码:6 / 10
页数:5
相关论文
共 31 条
[1]   Short-term effectiveness of radiochemoembolization for selected hepatic metastases with a combination protocol [J].
Akhlaghpoor, Shahram ;
Aziz-Ahari, Alireza ;
Amoui, Mahasti ;
Tolooee, Shahnaz ;
Poorbeigi, Hossein ;
Sheybani, Shahab .
WORLD JOURNAL OF GASTROENTEROLOGY, 2012, 18 (37) :5249-5259
[2]  
[Anonymous], [No title captured]
[3]   Oxaliplapin and Capecitabine (XELOX) Based Chemotherapy in the Treatment of Metastatic Colorectal Cancer: The Right Choice in Elderly Patients [J].
Berretta, Massimiliano ;
Aprile, Giuseppe ;
Nasti, Guglielmo ;
Urbani, Martina ;
Bearz, Alessandra ;
Lutrino, Stefania ;
Foltran, Luisa ;
Ferrari, Laura ;
Talamini, Renato ;
Fiorica, Francesco ;
Lleshi, Arben ;
Canzonieri, Vincenzo ;
Lestuzzi, Chiara ;
Borsatti, Eugenio ;
Fisichella, Rossella ;
Tirelli, Umberto .
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2013, 13 (09) :1344-1353
[4]   Colorectal Cancer in Elderly Patients: From Best Supportive Care to Cure [J].
Berretta, Massimiliano ;
Di Benedetto, Fabrizio ;
Di Francia, Raffaele ;
Lo Menzo, Emanuele ;
Palmeri, Sergio ;
De Paoli, Paolo ;
Tirelli, Umberto .
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2013, 13 (09) :1332-1343
[6]   Hepatocellular Carcinoma in HIV-Infected Patients: Check Early, Treat Hard [J].
Berretta, Massimiliano ;
Garlassi, Elisa ;
Cacopardo, Bruno ;
Cappellani, Alessandro ;
Guaraldi, Giovanni ;
Cocchi, Stefania ;
De Paoli, Paolo ;
Lleshi, Arben ;
Izzi, Immacolata ;
Torresin, Augusta ;
Di Gangi, Pietro ;
Pietrangelo, Antonello ;
Ferrari, Mariachiara ;
Bearz, Alessandra ;
Berretta, Salvatore ;
Nasti, Guglielmo ;
Di Benedetto, Fabrizio ;
Balestreri, Luca ;
Tirelli, Umberto ;
Ventura, Paolo .
ONCOLOGIST, 2011, 16 (09) :1258-1269
[7]   FOLFOX4 in the treatment of metastatic colorectal cancer in elderly patients: A prospective study [J].
Berretta, Massimiliano ;
Cappellani, Alessandro ;
Fiorica, Francesco ;
Nasti, Guglielmo ;
Frustaci, Sergio ;
Fisichella, Rossella ;
Bearz, Alessandra ;
Talamini, Renato ;
Lleshi, Arben ;
Tambaro, Rosa ;
Cocciolo, Alessandro ;
Ristagno, Maurizio ;
Bolognese, Antonio ;
Basile, Francesco ;
Meneguzzo, Nereo ;
Berretta, Salvatore ;
Tirelli, Umberto .
ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2011, 52 (01) :89-93
[8]   HIV-Positive Patients with Liver Metastases from Colorectal Cancer Deserve the Same Therapeutic Approach as the General Population [J].
Berretta, Massimiliano ;
Zanet, Ernesto ;
Basile, Francesco ;
Ridolfo, Anna L. ;
Di Benedetto, Fabrizio ;
Bearz, Alessandra ;
Berretta, Salvatore ;
Nasti, Guglielmo ;
Tirelli, Umberto .
ONKOLOGIE, 2010, 33 (04) :203-204
[9]  
Di Benedetto F, 2013, ANTI-CANCER AGENT ME, V13, P1354
[10]   Liver Resection for Colorectal Metastases in Older Adults: A Paired Matched Analysis [J].
Di Benedetto, Fabrizio ;
Berretta, Massimiliano ;
D'Amico, Giuseppe ;
Montalti, Roberto ;
De Ruvo, Nicola ;
Cautero, Nicola ;
Guerrini, Gian Piero ;
Ballarin, Roberto ;
Spaggiari, Mario ;
Tarantino, Giuseppe ;
Di Sandro, Stefano ;
Pecchi, Anna ;
Luppi, Gabriele ;
Gerunda, Giorgio-Enrico .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2011, 59 (12) :2282-2290