Synthesis of 2,3,5-substituted pyrrole derivatives

被引：28
作者：
Ferreira, PMT [1 ]
Maia, HLS [1 ]
Monteiro, LS [1 ]
机构：
[1] Univ Minho, Dept Chem, P-4700320 Braga, Portugal
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 25期
关键词：
dehydroalanine; dihydrofuran; pyrrole; dehydroproline;
D O I：
10.1016/S0040-4039(02)00810-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
2,3,5-Substituted pyrrole derivatives are prepared by treatment of 2,3-dihydrofuran derivatives with trifluoroacetic acid. These in turn are obtained by Michael addition of carbon nucleophiles of the beta-dicarbonyl type to N-(4-toluenesulfonyl)-N-(tert-butyloxycarbonyl)-dehydroalanine methyl ester. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：4491 / 4493
页数：3
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