Osteonecrosis of the Jaw and Concomitant Atypical Femoral Fractures with Bisphosphonates: A Comprehensive Literature Review

被引:6
作者
Aravamudan, Veeraraghavan Meyyur [1 ]
Er, Chaozer [1 ]
机构
[1] Woodlands Hlth Campus, Internal Med, Singapore, Singapore
关键词
osteonecrosis of jaw; atypical femoral fractures; bisphosphonates; MEDICATION-RELATED OSTEONECROSIS; RISK;
D O I
10.7759/cureus.5113
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Bisphosphonates are the first line of treatment for osteoporosis. Complications of bisphosphonates, such as osteonecrosis of the jaw (ONJ) and atypical femoral fractures (AFF), have been reported in the medical literature. Concomitant occurrence of both of these complications is very rare. In this review article, we will discuss the etiology, pathogenesis, and clinical studies, as well as case studies and their management per the latest clinical guidelines.
引用
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页数:6
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