Copper(II)-Catalyzed Domino Synthesis of 4-Benzenesulfonyl Isoxazoles from 2-Nitro-1,3-enynes, Amines, and Sodium Benzenesulfinate

被引：5

作者：

Ge, Junying ^{[1
,2
,3
,4
]}

Ding, Qiuping ^{[1
,2
]}

Long, Xujing ^{[1
,2
]}

Liu, Xuan ^{[1
,2
]}

Peng, Yiyuan ^{[1
,2
]}

机构：

[1] Jiangxi Normal Univ, Key Lab Funct Small Organ Mol, Minist Educ, Jiangxi Key Lab Green Chem, Nanchang 330022, Jiangxi, Peoples R China

[2] Jiangxi Normal Univ, Coll Chem & Chem Engn, Nanchang 330022, Jiangxi, Peoples R China

[3] Yichun Univ, Inst Coordinat Catalysis, Engn Ctr Jiangxi, Univ Lithium Energy,Jiangxi Univ Appl Chem & Chem, Yichun 336000, Jiangxi, Peoples R China

[4] Yichun Univ, Key Lab, Jiangxi Univ Appl Chem & Chem Biol, Yichun 336000, Jiangxi, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 85卷 / 21期

基金：

中国国家自然科学基金;

关键词：

Catalysis - Sodium - Copper compounds;

D O I：

10.1021/acs.joc.0c01964

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and effective method for the synthesis of fully substituted 4-benzenesulfonyl isoxazoles through a copper(II)-catalyzed three-component reaction of 2-nitro-1,3-enynes, amines, and sodium benzenesulfinate is described. The reaction proceeds smoothly under mild conditions and provides the benzenesulfonyl isoxazoles with high chemoselectivity.

引用

页码：13886 / 13894

页数：9

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