Active and inactive protein kinases: Structural basis for regulation

被引：1182

作者：

Johnson, LN ^{[1
]}

Noble, MEM ^{[1
]}

Owen, DJ ^{[1
]}

机构：

[1] UNIV OXFORD,OXFORD CTR MOLEC SCI,OXFORD OX1 3QU,ENGLAND

来源：

CELL | 1996年 / 85卷 / 02期

关键词：

D O I：

10.1016/S0092-8674(00)81092-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：149 / 158

页数：10

共 38 条

[1] PHOSPHORYLATION MODULATES CATALYTIC FUNCTION AND REGULATION IN THE CAMP-DEPENDENT PROTEIN-KINASE [J].

ADAMS, JA ;

MCGLONE, ML ;

GIBSON, R ;

TAYLOR, SS .

BIOCHEMISTRY, 1995, 34 (08) :2447-2454

[2] DIVALENT METAL-IONS INFLUENCE CATALYSIS AND ACTIVE-SITE ACCESSIBILITY IN THE CAMP-DEPENDENT PROTEIN-KINASE [J].

ADAMS, JA ;

TAYLOR, SS .

PROTEIN SCIENCE, 1993, 2 (12) :2177-2186

[3]

AHN NG, 1991, J BIOL CHEM, V266, P4220

[4] PHOSPHOTRANSFERASE AND SUBSTRATE BINDING MECHANISM OF THE CAMP-DEPENDENT PROTEIN-KINASE CATALYTIC SUBUNIT FROM PORCINE HEART AS DEDUCED FROM THE 2.0 ANGSTROM STRUCTURE OF THE COMPLEX WITH MN2+ ADENYLYL IMIDODIPHOSPHATE AND INHIBITOR PEPTIDE PKI(5-24) [J].

BOSSEMEYER, D ;

ENGH, RA ;

KINZEL, V ;

PONSTINGL, H ;

HUBER, R .

EMBO JOURNAL, 1993, 12 (03) :849-859

[5] THE CRYSTAL-STRUCTURE OF CYCLIN-A [J].

BROWN, NR ;

NOBLE, MEM ;

ENDICOTT, JA ;

GARMAN, EF ;

WAKATSUKI, S ;

MITCHELL, E ;

RASMUSSEN, B ;

HUNT, T ;

JOHNSON, LN .

STRUCTURE, 1995, 3 (11) :1235-1247

[6]

CARMEL G, 1994, J BIOL CHEM, V269, P7304

[7] DOMAIN MOVEMENTS IN PROTEIN-KINASES [J].

COX, S ;

RADZIOANDZELM, E ;

TAYLOR, SS .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 1994, 4 (06) :893-901

[8] Kinetic analysis of cAMP-dependent protein kinase: Mutations at histidine 87 affect peptide binding and pH dependence [J].

Cox, S ;

Taylor, SS .

BIOCHEMISTRY, 1995, 34 (49) :16203-16209

[9] EXPRESSION OF THE PHOSPHORYLASE KINASE-GAMMA SUBUNIT CATALYTIC DOMAIN IN ESCHERICHIA-COLI [J].

COX, S ;

JOHNSON, LN .

PROTEIN ENGINEERING, 1992, 5 (08) :811-819

[10] CHARACTERIZATION OF THE REGULATORY DOMAIN OF THE GAMMA-SUBUNIT OF PHOSPHORYLASE-KINASE - THE 2 NONCONTIGUOUS CALMODULIN-BINDING SUBDOMAINS ARE ALSO AUTOINHIBITORY [J].

DASGUPTA, M ;

BLUMENTHAL, DK .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (38) :22283-22289

← 1 2 3 4 →