Enantiomeric separation of three chiral drugs by nonaqueous capillary electrophoresis with triethylamine as additive

被引：13
|
作者：
Ren, XQ
Huang, AJ
Wang, TS
Sun, YL [1 ]
Sun, ZP
机构：
[1] Peking Univ, Dept Chem, Beijing 100871, Peoples R China
[2] Natl Inst Control Pharmaceut & Biol Prod, Beijing 100050, Peoples R China
来源：
CHROMATOGRAPHIA | 1999年 / 50卷 / 9-10期
关键词：
capillary electrophoresis; enantioseparation; non-aqueous media; triethylamine;
D O I：
10.1007/BF02493671
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The enantiomeric separation of chiral drugs by capillary electrophoresis (CE) in nonaqueous system has been investigated. Successful separation of bepridil, ondansetron and pinacidil in formamide using beta-cyclodextrin as chiral selector were achieved. The addition of triethylamine into the background electrolyte enhanced the enantiomeric discrimination.
引用
收藏
页码：625 / 628
页数：4
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