Perspectives of Regenerative Mechanisms in Cardiovascular Disease Spotlighting Endothelial Progenitor Cells

被引：1

作者：

Steinmetz, Martin ^{[1
]}

Nickenig, Georg ^{[1
]}

Werner, Nikos ^{[1
]}

机构：

[1] Univ Klinikum Bonn, Med Klin & Poliklin 2, D-53105 Bonn, Germany

来源：

MEDIZINISCHE KLINIK | 2009年 / 104卷 / 04期

关键词：

Endothelial progenitor cells; Atherosclerosis; Regenerative medicine; Mobilization; Coronary heart disease; ACUTE MYOCARDIAL-INFARCTION; COLONY-STIMULATING FACTOR; CORONARY-ARTERY-DISEASE; BONE-MARROW-CELLS; HEMATOPOIETIC STEM-CELLS; NITRIC-OXIDE SYNTHASE; FOLLOW-UP; INTRACORONARY INFUSION; NEOINTIMA FORMATION; TRAINING INCREASES;

D O I：

10.1007/s00063-009-1054-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cardiovascular diseases are the most common cause of death in the Western world. In general, the underlying disease is atherosclerosis, which is hallmarked by deterioration of the endothelial monolayer. Restoration of an intact endothelial monolayer for prevention and therapy of cardiovascular diseases is one key concept of regenerative medicine. This article offers a review of state-of-the-art regenerative mechanisms in cardiovascular disease spotlighting endothelial progenitor cells, and further features the perspectives of regenerative medicine in vascular biology.

引用

页码：287 / 295

页数：9