Diversity of homology-dependent gene silencing strategies in fungi

被引：37
作者：
Faugeron, G
机构：
[1] Univ Paris 07, CNRS, UMR 7592, Inst Jacques Monod, F-75251 Paris 05, France
[2] Univ Paris 06, F-75251 Paris, France
来源：
CURRENT OPINION IN MICROBIOLOGY | 2000年 / 3卷 / 02期
关键词：
D O I：
10.1016/S1369-5274(00)00066-7
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The experimental introduction of DIVA in fungi has revealed a variety of gene inactivation strategies triggered in response to the presence of homologous nucleic acid sequences. These homology effects reveal distinct classes of gene inactivation resulting from hypermutation or relying on regulatory mechanisms that operate at either the transcriptional or the post-transcriptional level.
引用
收藏
页码：144 / 148
页数：5
相关论文
共 47 条
[21]   The DNA methylation paradox [J].
Jones, PA .
TRENDS IN GENETICS, 1999, 15 (01) :34-37
[22]  
KINSEY JA, 1994, GENETICS, V138, P657
[23]   DUPLICATION-TARGETED DNA METHYLATION AND MUTAGENESIS IN THE EVOLUTION OF EUKARYOTIC CHROMOSOMES [J].
KRICKER, MC ;
DRAKE, JW ;
RADMAN, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (03) :1075-1079
[24]   An inverted repeat triggers cytosine methylation of identical sequences in Arabidopsis [J].
Luff, B ;
Pawlowski, L ;
Bender, J .
MOLECULAR CELL, 1999, 3 (04) :505-511
[25]   Masc2, a gene from Ascobolus encoding a protein with a DNA-methyltransferase activity in vitro, is dispensable for in vivo methylation [J].
Malagnac, F ;
Grégoire, A ;
Goyon, C ;
Rossignol, JL ;
Faugeron, G .
MOLECULAR MICROBIOLOGY, 1999, 31 (01) :331-338
[26]   A gene essential for de novo methylation and development in ascobolus reveals a novel type of eukaryotic DNA methyltransferase structure [J].
Malagnac, F ;
Wendel, B ;
Goyon, C ;
Faugeron, G ;
Zickler, D ;
Rossignol, JL ;
NoyerWeidner, M ;
Vollmayr, P ;
Trautner, TA ;
Walter, J .
CELL, 1997, 91 (02) :281-290
[27]   Suppression of crossing-over by DNA methylation in Ascobolus [J].
Maloisel, L ;
Rossignol, JL .
GENES & DEVELOPMENT, 1998, 12 (09) :1381-1389
[28]   RNA-mediated RNA degradation and chalcone synthase A silencing in Petunia [J].
Metzlaff, M ;
ODell, M ;
Cluster, PD ;
Flavell, RB .
CELL, 1997, 88 (06) :845-854
[29]   EVIDENCE FOR CYTOSINE METHYLATION OF NONSYMMETRICAL SEQUENCES IN TRANSGENIC PETUNIA-HYBRIDA [J].
MEYER, P ;
NIEDENHOF, I ;
TENLOHUIS, M .
EMBO JOURNAL, 1994, 13 (09) :2084-2088
[30]   EPIMUTATION OF REPEATED GENES IN ASCOBOLUS-IMMERSUS [J].
RHOUNIM, L ;
ROSSIGNOL, JL ;
FAUGERON, G .
EMBO JOURNAL, 1992, 11 (12) :4451-4457
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