Rate-dependent changes in atrial action potential duration after short-duration rapid atrial pacing in humans

被引:4
作者
Watanabe, I [1 ]
Masaki, R [1 ]
Ohkubo, K [1 ]
Okumura, Y [1 ]
Yamada, T [1 ]
Oshikawa, N [1 ]
Saito, S [1 ]
Ozawa, Y [1 ]
Kanmatsuse, K [1 ]
机构
[1] Nihon Univ, Sch Med, Dept Med 2, Itabashi Ku, Tokyo 1738610, Japan
关键词
atrial fibrillation; electrical remodeling; monophasic action potential;
D O I
10.1253/circj.66.874
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The effect of rapid atrial pacing on the rate adaptation of the atrial action potential duration was studied in humans. The right atrial monophasic action potential (RAMAP) of 5 patients was recorded before and after 30min of rapid atria] pacing. The pacing cycle length (CL) was 146 9ms, the shortest duration at which 1:1 capture was possible. The RAMAP duration at 90% repolarization (RMAPD) was measured. CL-dependent changes in RAMAPD (CL 600 ms-CL 300 ms) before and after rapid atrial pacing were 51.8 +/- 10.7 ms and 30.8 +/- 7.6 ms (p<0.05), respectively.
引用
收藏
页码:874 / 875
页数:2
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