Identification of an esterase from Bacillus acidocaldarius with sequence similarity to a hormone sensitive lipase subfamily

被引：0
|
作者：
Manco, G
Adinolfi, E
Pisani, FM
Carratore, V
Rossi, M
机构：
[1] CNR,IST BIOCHIM PROT & ENZIMOL,I-80125 NAPLES,ITALY
[2] UNIV NAPLES,I-80100 NAPLES,ITALY
来源：
PROTEIN AND PEPTIDE LETTERS | 1997年 / 4卷 / 06期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We purified an esterase from Bacillus acidocaldarius whose NH2-terminal sequence corresponds to an open reading frame (ORF) previously reported to show homology with the mammalian hormone sensitive lipase (HSL)-like subgroup of the esterase/lipase family. The enzyme displays esterase but not lipase activity. For this enzyme we predicted the alpha/beta-hydrolase topological fold common to several esterases and lipases and identified Set 155, Asp 252 and His 282 as the putative members of the catalytic triad.
引用
收藏
页码：375 / 382
页数：8
相关论文
共 50 条
  • [21] Structural and functional analysis of a novel EstE5 belonging to the subfamily of hormone-sensitive lipase
    Nam, Ki Hyun
    Kim, Min-Young
    Kim, Soo-Jin
    Priyadarshi, Amit
    Lee, Won Ho
    Hwang, Kwang Yeon
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 379 (02) : 553 - 556
  • [22] IDENTIFICATION AND ROLE OF THE BASAL PHOSPHORYLATION SITE ON HORMONE-SENSITIVE LIPASE
    GARTON, AJ
    YEAMAN, SJ
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 1990, 191 (01): : 245 - 250
  • [23] INHIBITION OF AN ADIPOSE TISSUE LIPASE BY PHENTOLAMINE AND DIBENZYLINE AND ITS POSSIBLE IDENTIFICATION AS HORMONE SENSITIVE LIPASE
    LECH, JJ
    CALVERT, DN
    FEDERATION PROCEEDINGS, 1968, 27 (02) : 242 - &
  • [24] SEQUENCE SIMILARITIES BETWEEN HORMONE-SENSITIVE LIPASE AND 5 PROKARYOTIC ENZYMES
    LANGIN, D
    HOLM, C
    TRENDS IN BIOCHEMICAL SCIENCES, 1993, 18 (12) : 466 - 467
  • [25] REGULATION OF STEROIDOGENESIS IN RAT ADRENAL-GLAND - IDENTIFICATION OF THE BIFUNCTIONAL, HORMONE-SENSITIVE CHOLESTEROL ESTERASE TRIACYLGLYCEROL LIPASE ENZYME PROTEIN AND ITS DISCRIMINATION FROM HORMONE-INSENSITIVE LIPASES
    TRZECIAK, WH
    SONNENBORN, U
    BALKOW, C
    KUNAU, WH
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1984, 35 (2-3) : 131 - 141
  • [26] DOES SEQUENCE SIMILARITY OF HUMAN CHOLINE ESTERASE, TORPEDO ACETYLCHOLINE ESTERASE AND GEOTRICHUM-CANDIDUM LIPASE REVEAL THE ACTIVE-SITE SERINE RESIDUE
    SLABAS, AR
    WINDUST, J
    SIDEBOTTOM, CM
    BIOCHEMICAL JOURNAL, 1990, 269 (01) : 279 - 280
  • [27] The porcine hormone-sensitive lipase gene: sequence, structure, polymorphisms and linkage mapping
    Harbitz, I
    Langset, M
    Ege, AG
    Hoyheim, B
    Davies, W
    ANIMAL GENETICS, 1999, 30 (01) : 10 - 15
  • [28] ISOLATION OF A PHOSPHOPEPTIDE FROM BOVINE HORMONE-SENSITIVE LIPASE
    GARTON, AJ
    YEAMAN, SJ
    CAMPBELL, DG
    BIOCHEMICAL SOCIETY TRANSACTIONS, 1987, 15 (03) : 491 - 492
  • [29] Crystal structure of PMGL2 esterase from the hormone-sensitive lipase family with GCSAG motif around the catalytic serine
    Boyko, Konstantin M.
    Kryukova, Marya, V
    Petrovskaya, Lada E.
    Nikolaeva, Alena Y.
    Korzhenevsky, Dmitry A.
    Novototskaya-Vlasova, Ksenia A.
    Rivkina, Elizaveta M.
    Dolgikh, Dmitry A.
    Kirpichnikov, Mikhail P.
    Popov, Vladimir O.
    PLOS ONE, 2020, 15 (01):
  • [30] PURIFICATION OF ADIPOCYTE HORMONE-SENSITIVE LIPASE AND ADRENAL CHOLESTEROL ESTERASE - A GENERAL PROTEIN-PURIFICATION STRATEGY
    CHANG, MK
    EGAN, JJ
    LONDOS, C
    FEDERATION PROCEEDINGS, 1986, 45 (06) : 1670 - 1670
12345