This article focuses on progress of syntheses of materials by sold state reaction at low-heating temperatures. By now, there are sixteen application fields: 1. Cluster and nonlinear optical materials; 2. Polyoxyanion compounds; 3. Nanomaterials; 4. Electric materials; 5. Super conducting materials; 6. Semiconductors; 7. Materials of corrosion resistance 8. Phosphates; 9. Gas sensor materials; 10. Thermochromism materials; 11. Ceramic materials; 12. Catalyzer and catalyzed reaction; 13. Organometallic compounds; 14. Inorganic coordination compounds; 15. Organic reactions and organic compounds; 16. Others. To be a simple, convenient, less solvents involved, high yield, save energy, environmental friendly, and cheap synthetic method to these materials, the application of solid state reaction at low-heating temperatures is an important developing direction of green chemistry.