A minor groove binding track in reverse transcriptase

被引：112

作者：

Bebenek, K

Beard, WA

Darden, TA

Li, LP

Prasad, R

Luxon, BA

Gorenstein, DG

Wilson, SH

Kunkel, TA

机构：

[1] NIEHS, STRUCT BIOL LAB, RES TRIANGLE PK, NC 27709 USA

[2] NIEHS, LAB COMPUTAT BIOL & RISK ANAL, RES TRIANGLE PK, NC 27709 USA

[3] SEALY CTR MOL SCI, GALVESTON, TX 77555 USA

[4] UNIV TEXAS, MED BRANCH, SEALY CTR STRUCT BIOL, GALVESTON, TX 77555 USA

来源：

NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 03期

关键词：

D O I：

10.1038/nsb0397-194

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Evidence is presented indicating that processive synthesis by HIV-1 reverse transcriptase involves interactions between the minor groove of the template-primer and a discrete protein structural element, the minor groove binding track (MGBT).

引用

页码：194 / 197

页数：4

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