Nitrative Cyclization of 1-Ethynyl-2-(vinyloxy)benzenes to Access 1-[2-(Nitromethyl)benzofuran-3-yl] Ketones Through Dioxygen Activation

被引：67
作者：
Hu, Ming [1 ]
Liu, Bang [1 ]
Ouyang, Xuan-Hui [1 ]
Song, Ren-Jie [1 ]
Li, Jin-Heng [1 ,2 ]
机构：
[1] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China
[2] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2015年 / 357卷 / 14-15期
关键词：
cyclization; dioxygen activation; enynes; nitration; CATALYZED CASCADE CYCLIZATION; FREE NITRO-CARBOCYCLIZATION; TERT-BUTYL NITRITE; CARBON TRIPLE BOND; C-C; RADICAL-ADDITION; ELECTROPHILIC ACTIVATION; AEROBIC OXYGENATION; MOLECULAR-OXYGEN; TERMINAL ALKYNES;
D O I：
10.1002/adsc.201500336
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new metal-free method for the nitrative cyclization of 1-ethynyl-2-(vinyloxy) benzenes with tert-butyl nitrite (t-BuONO), air and water at room temperature is presented, in which an oxygen atom is introduced into the carbon-carbon triple bond to form a new carbonyl group through dioxygen activation.
引用
收藏
页码：3332 / 3340
页数：9
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