A tri-serine tri-lactone scaffold for the quantification of citrate in urine

被引：16

作者：

Akdeniz, Ali ^{[1
,2
]}

Caglayan, Mehmet Gokhan ^{[1
,2
,3
]}

Anzenbacher, Pavel, Jr. ^{[1
,2
]}

机构：

[1] Bowling Green State Univ, Dept Chem, Bowling Green, OH 43403 USA

[2] Bowling Green State Univ, Ctr Photochem Sci, Bowling Green, OH 43403 USA

[3] Ankara Univ, Fac Pharm, Dept Analyt Chem, TR-06100 Ankara, Turkey

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 09期

关键词：

SENSOR; RECOGNITION; RECEPTORS; BINDING; MALATE;

D O I：

10.1039/c5cc08759g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Tri-serine tri-lactone based C-3 symmetry fluorescent sensors were synthesized. Citrate is shown to bind to sensors, while displaying an increase in fluorescence intensity for the sensor with thiourea and a quenching for the sensor with sulfonamide. Information-rich responses of the sensors enable us to discriminate structurally similar anions, including mono-, di- and tri-carboxylates with 100% correct classification. A simple two-sensor array enables the determination of the concentration of citrate in urine without any sample preparation with high accuracy (error < 2%).

引用

收藏

页码：1827 / 1830

页数：4

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