Design, Fabrication, and Assembly of an Optical Biosensor Probe Package for OCT (Optical Coherence Tomography) Application

被引:8
|
作者
Premachandran, C. S. [1 ]
Khairyanto, Ahmad [1 ]
Sheng, Kelvin Chen Wei [1 ]
Singh, Janak [1 ]
Teo, Jason [1 ]
Xu Yingshun [2 ]
Chen Nanguang [2 ]
Sheppard, Colin [2 ]
Olivo, Malini [3 ,4 ]
机构
[1] ASTAR, Inst Microelect, Singapore 117685, Singapore
[2] Natl Univ Singapore, Dept Bioengn, Singapore 117576, Singapore
[3] Natl Canc Ctr, Div Med Sci, Singapore 1696190, Singapore
[4] ASTAR, Bioopt Imaging Grp, Singapore Bioimaging Consortium, Singapore 138667, Singapore
来源
关键词
Biosensor; micro-electro-mechanical system (MEMS); MEMS packaging; micromirror; optical coherence tomography (OCT); optical probe; silicon optical bench (SiOB); 3-D MEMS;
D O I
10.1109/TADVP.2009.2013658
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A miniaturized optical bioprobe package is developed using a 3-D micromirror and is tested for bio-imaging application. A silicon optical bench is designed and micromachined to assemble the fiber, lens, and the 3-D micromirror device. A 45 degrees angle trench is used to place the micromirror to achieve larger scanning range. Trace lines are formed on the optical bench and are connected to silicon micromirror using solder. A GRIN lens with lower numerical aperture has been used to focus the optical beam onto the micromirror. The bioprobe is packaged and is tested in a time domain optical coherence tomography (OCT) setup and optical image is obtained for plant tissue.
引用
收藏
页码:417 / 422
页数:6
相关论文
共 50 条
  • [1] Design, fabrication and assembly of an optical biosensor probe package for OCT (optical coherence tomography) application
    Premachandran, C. S.
    Sheng, Kelvin Chen Wei
    Singh, Janak
    Teo, Jason
    Yingshun, Xu
    Nanguang, Chen
    Sheppard, Colin
    Olivo, Malini
    57TH ELECTRONIC COMPONENTS & TECHNOLOGY CONFERENCE, 2007 PROCEEDINGS, 2007, : 1556 - +
  • [2] Optical alignment of dual-axis MEMS based scanning optical probe for Optical Coherence Tomography (OCT) application
    Khairyanto, Ahmad
    Premachandran, C. S.
    Chen, Kelvin W. S.
    Singh, Janak
    Chandrappan, Jayakrishnan
    Lau, John H.
    Xu, Yingshun
    EPTC: 2008 10TH ELECTRONICS PACKAGING TECHNOLOGY CONFERENCE, VOLS 1-3, 2008, : 945 - 950
  • [3] Optical coherence tomography (OCT)
    Liebmann, J
    Bowd, C
    Medeiros, FA
    Schuman, J
    GLAUCOMA DIAGNOSIS STRUCTURE AND FUNCTION, 2004, : 71 - 82
  • [4] Study on an all-fiber optical coherence tomography (OCT) probe
    Huang, Xiaoqian
    Tong, X. L.
    OPTICAL FIBER TECHNOLOGY, 2023, 79
  • [5] Optical probe design with extended depth-of-focus for optical coherence microscopy and optical coherence tomography
    Lee, Seungwan
    Choi, Minseog
    Lee, Eunsung
    Jung, Kyu-Dong
    Chang, Jong-hyeon
    Kim, Woonbae
    MOEMS AND MINIATURIZED SYSTEMS XII, 2013, 8616
  • [6] Application of optical coherence tomography (OCT) to nondestructive inspection of dentures
    Sumi, Yasunori
    Ozawa, Nobuyoshi
    Nagaosa, Shuichiro
    Minakuchi, Shunsuke
    Umemura, Osami
    ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2011, 53 (02) : 237 - 241
  • [7] Special Feature Development and Application of Optical Coherence Tomography (OCT)
    Pircher, Michael
    APPLIED SCIENCES-BASEL, 2017, 7 (10):
  • [8] Application of optical coherence tomography (OCT) in middle ear surgery
    Heermann, R
    Hauger, C
    Issing, PR
    Lenarz, T
    LARYNGO-RHINO-OTOLOGIE, 2002, 81 (06): : 400 - 405
  • [10] Optical coherence tomography (OCT): A review
    Schmitt, JM
    IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 1999, 5 (04) : 1205 - 1215