Imaging superficial tissues with polarized light

被引:5
作者
Jacques, SL
Roman, JR
Lee, K
机构
[1] Providence St Vincent Med Ctr, Oregan Med Laser Ctr, Portland, OR 97225 USA
[2] Oregon Grad Inst, Beaverton, OR 97006 USA
[3] Oregon Hlth & Sci Univ, Portland, OR 97201 USA
关键词
imaging; polarized light; tissue optical properties; muscle; liver; polystyrene microspheres;
D O I
10.1002/(SICI)1096-9101(2000)26:2<119::AID-LSM3>3.3.CO;2-P
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Objective: Polarized light can be used to obtain images of superficial tissue layers such as skin, and some example images are presented. This study presents a study of the transition of linearly polarized light into randomly polarized light during light propagation through tissues. Study Design/Materials and Methods: The transition of polarization was studied in polystyrene microsphere solutions, in chicken muscle (breast) and liver, and in porcine muscle and skin. The transition is discussed in terms of a diffusion process characterized by an angular diffusivity (radians(2)/mean free path) for the change in angular orientation of linearly polarized light per unit optical path traveled by the light. Results: Microsphere diffusivity increased from 0.031 to 0.800 for diameters decreasing from 6.04 mu m to 0.306 mu m, respectively. Tissue diffusivity varied from a very low value (0.0004) for chicken liver to an intermediate value (0.055) for chicken and porcine muscle to a very high value (0.78) for pig skin. Conclusion: The results are consistent with the hypothesis that birefringent tissues randomize linearly polarized light more rapidly than nonbirefringent tissues. The results suggest that polarized light imaging of skin yields images based only on photons backscattered from the superficial epidermal and initial papillary dermis because the birefringent dermal collagen rapidly randomizes polarized light. This anatomic region of the skin is where cancer commonly arises. (C) 2000 Wiley-Liss, Inc.
引用
收藏
页码:119 / 129
页数:11
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