Glucose-based novel gemini surfactants: Surface activities, aggregation properties and a preliminary study as nanocarrier for resveratrol

被引:24
作者
Gan, Changsheng [1 ]
Cai, Kunliang [1 ]
Qu, Xilin [1 ]
Li, Hong [1 ]
Wei, Lianggang [1 ]
Cheng, Rong [1 ]
机构
[1] Hefei Univ Technol, Sch Food Sci & Engn, Minist Educ, Engn Res Ctr Bioproc, Hefei 230009, Anhui, Peoples R China
关键词
Gemini surfactants; Surface activity; Glucose; Micellization; Vesicle; Resveratrol; TO-MICELLE TRANSITION; ALKYL TAIL LENGTH; ENTRAPPED NIOSOMES; CO-ENCAPSULATION; IN-VITRO; ADSORPTION; MICELLIZATION; BEHAVIOR; TENSION; GLUCONAMIDE;
D O I
10.1016/j.molliq.2019.03.153
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
In combination with the advantages of gemini surfactants and sugar-based surfactants, a novel group of glucose derived gemini surfactants was synthesized and their surface properties were investigated. Some products could reduce the surface tension to 24.8-34.2 mN/m at the concentration level of 10(-5) mol/L. Their aggregation behaviors were further studied by means of dynamic light scattering, X-ray diffraction and transmission electron microscopy. The results indicated that the investigated surfactants could self-assemble into vesides in a wide range of concentrations. Since vesicles are widely used as nanocarrier in cosmetic and pharmaceutical field, the gemini surfactant 1c-based vesicles encapsulating resveratrol (RSV) as model compound were studied, and the results revealed that the vesicles displayed high loading capacity for RSV. (C) 2019 Elsevier B.V. All rights reserved.
引用
收藏
页码:781 / 787
页数:7
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