Intraoperative mitomycin-C versus postoperative topical mitomycin-C drops for the treatment of pterygium

被引:0
作者
Helal, M [1 ]
Messiha, N [1 ]
Amayem, A [1 ]
ElMaghraby, A [1 ]
Elsherif, Z [1 ]
Dabees, M [1 ]
机构
[1] RES INST OPHTHALMOL,CAIRO,EGYPT
来源
OPHTHALMIC SURGERY AND LASERS | 1996年 / 27卷 / 08期
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中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
BACKGROUND AND OBJECTIVE: To evaluate the safety and efficacy of two different regimens of mitomycin-C (MMC) application as adjunctive chemotherapy in the treatment of pterygia. PATIENTS AND METHODS: One hundred fifty-six patients underwent pterygium excision using the bare sclera technique. They were randomly assigned to have either 0.1 mg/ml of MMC applied to the bare sclera for 3 minutes intraoperatively, or 0.05-mg/ml drops applied topically for 2 weeks postoperatively. The mean follow-up period was 11 months (range 7 to 17). RESULTS: Complications with the intraoperative MMC included 5 cases of recurrence (5.75%), 2 cases of superficial punctate keratitis (SPK), and 3 cases of delayed conjunctival wound healing. Topical MMC led to 6 cases of recurrence (6.9%), 5 cases of SPK, 4 cases of delayed conjunctival wound healing, and 2 cases of mild iritis. CONCLUSION: A single, intraoperative application of MMC is a simple, effective alternative adjunctive treatment for pterygium.
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页码:674 / 678
页数:5
相关论文
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