Zinc oxide nanoparticles: potential novel applications in cellular physiology, pathology, neurosciences and cancer research

被引:18
作者
Pantic, Senka [2 ]
Skodric, Sanja Radojevic [3 ]
Loncar, Zlatibor [4 ]
Pantic, Igor [1 ]
机构
[1] Univ Belgrade, Fac Med, Inst Med Physiol, Lab Cellular Physiol, Visegradska 26-2, RS-11129 Belgrade, Serbia
[2] Univ Belgrade, Inst Histol & Embryol, Sch Med, Visegradska 26-2, RS-11129 Belgrade, Serbia
[3] Univ Belgrade, Inst Pathol, Fac Med, Dr Subotica 1, RS-11129 Belgrade, Serbia
[4] Univ Belgrade, Emergency Ctr, Clin Ctr Serbia, Fac Med, Pasterova 2, RS-11000 Belgrade, Serbia
关键词
Zinc; Nanomaterial; Toxicity; Gene; Signaling; ZNO NANOPARTICLES; SILVER NANOPARTICLES; INDUCE APOPTOSIS; DRUG-DELIVERY; CELLS; EXPRESSION; EXPOSURE; DECREASE;
D O I
10.1515/rams-2019-0002
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
With the rapid development of nanotechnology during the past several years, attention has been focused on metallic nanomaterials, due to their specific physical and chemical characteristics. Zinc oxide nanoparticles (ZnO NPs) have numerous potential applications in industry, as a part of various consumer products, but also in medical research. Anticancer properties of ZnO NPs have been suggested in cell cultures, however, the precise mechanism responsible for their activity in these conditions remains elusive. Cytotoxicity and genotoxicity of ZnO NPs are also unclear. Apart from cancer research, ZnO NPs are today widely researched in almost all areas of fundamental medicine. In this short review, we discuss recently published articles on ZnO NPs applications in cellular physiology, pathology, neurosciences and oncology.
引用
收藏
页码:17 / 21
页数:5
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